【摘要】 舒更葡糖(SUG)是一种新型非去极化肌松药拮抗药,对罗库溴铵和维库溴铵等甾体类非去极化肌松药物具有特异性的快速的拮抗作用,其效果优于乙酰胆碱酯酶抑制剂。可用于合并脏器功能障碍、重症肌无力、困难气道以及特殊人群等患者。本文对其作用机制、药代动力学特点、临床应用及安全性和不良反应进行综述。更多还原

【Abstract】 Sugammadex(SUG) is a new type of non-depolarizing muscle relaxant antagonist, which has a specific and rapid antagonistic effect on steroidal non-depolarizing muscle relaxants such as rocuronium and vecuronium, and its effect is better than that of acetylcholinesterase inhibitors. It can be used in patients with organ dysfunction, myasthenia gravis, difficult airway or special groups of patients. The mechanism, pharmacokinetic characteristics, clinical application, safety and adverse reactions of SUG are reviewed in this paper.更多还原