【摘要】 目的:探讨在SPECT唾液腺显像中分别进行前、后位图像采集获得腮腺功能参数的差异。方法:对64例患者应用SPECT进行对向双探头前、后位⁹⁹Tc^mO₄^-唾液腺动态显像（SGS）。勾画腮腺ROI,获得腮腺净计数(Count_net),并计算前、后位腮腺15 min摄取率(UR₁₅)及酸刺激后排泌分数（EF）,使用Wilcoxon秩和检验分别比较前后位15 min腮腺净计数(Count_net15)、酸刺激前最大净计数值(Count_max)、腮腺UR₁₅及EF。结果:前、后位图像中,左腮腺Count_net15分别为2.46±1.29、2.92±1.70（Z=-3.42,P=0.01）,右侧分别为2.82±1.55、3.06±1.76（Z=-2.25,P=0.03）;左侧腮腺酸刺激前Count_max分别为2.79±1.50、3.23±1.87（Z=-3.09,P<0.01）,右侧分别为3.20±1.69、3.48±1.92（Z=-2.17,P=0.03）。前、后位图像中左侧UR₁₅分别为（1.71±0.76）%、（2.74±1.38）%（Z=-6.34,P<0.01）,右侧分别为（1.97±1.01）%、（2.86±1.45）%（Z=-6.11,P<0.01）;左侧EF分别为（74.84±14.81）%、（76.61±15.91）%（Z=-3.92,P<0.01）,右侧分别为（71.17±15.34）%、（71.48±14.90）%（Z=-4.68,P<0.01）。双侧腮腺后位Count_net15、酸刺激前Count_max均高于前位,且差异有统计学意义;双侧腮腺前位UR₁₅均高于后位,且差异有统计学意义;双侧腮腺后位EF均低于前位且差异有统计学意义。结论:前、后位采集腮腺动态显像所获得的摄取及排泌参数均有差异,差异是下颌支的骨性衰减所导致。更多还原

【Abstract】 Objective: To investigate the difference of the functional parameters of the parotid glands obtained by the anterior and posterior scanning in SPECT salivary glands scintigraphy（SGS）. Methods: Sixty-four patients underwent SGS, which was performed by dual-detector SPECT with ⁹⁹Tc^mO₄^-. The parotid ROI was delineated to obtain the net counts of parotid glands(Count_net). The 15 min uptake ratio(UR₁₅) of the parotid gland, and the excretion fraction（EF） after acid stimulation at the anterior and posterior imaging were calculated. The Wilcoxon rank-sum test was used to compare the difference in the 15 min net counts(Count_net15), the maximum net count before acid stimulation(Count_max) of the parotid glands, the UR₁₅ and EF of the anterior and posterior scanning, respectively. Results: In the anterior and posterior images, the Count_net15 of the left parotid gland were 2.46±1.29 vs. 2.92±1.70（Z=-3.42, P=0.01）, and the right ones were 2.82±1.55 vs. 3.06±1.76, respectively（Z=-2.25,P=0.03）. The Count_maxof left parotid gland were 2.79±1.50 vs. 3.23±1.87（Z=-3.09, P<0.01）, and the right ones were 3.20±1.69 vs. 3.48±1.92（Z=-2.17, P=0.03）. The UR₁₅ of the left parotid at the anterior and posterior images were（1.71 ±0.76）% vs.（2.74 ±1.38）%（Z =-6.34, P <0.01）, and the right were（1.97 ±1.01）% vs.（2.86 ±1.45）%（Z =-6.11, P <0.01）. The EF of the left parotid were（74.84±14.81）% vs.（76.61 ±15.91）%（Z =-3.92, P <0.01）, and the right were（71.17 ±15.34）% vs.（71.48 ±14.90）%（Z=-4.68, P<0.01）. The Count_net15 and Count_maxof both parotid glands in the posterior images were significantly higher than the anterior ones. The anterior UR₁₅ of both parotid glands were significantly higher than that in the posterior ones. The EF of both parotids in the posterior images were significantly lower than that in the anterior. Conclusion: There are differences in the uptake and excretion of parotid glands dynamic imaging between the anterior and posterior scanning. The difference is caused by the osseous attenuation of the mandibular branch.更多还原