【摘要】 目的探讨甲状腺结节钙化的特点,分析老年甲状腺结节患者钙化形态与分布特征,以提高甲状腺良恶性结节的诊断正确性。方法回顾性分析上海中医药大学附属曙光医院近5年经病理证实的常见的各类甲状腺结节69例,包括甲状腺癌(13例)、腺瘤(22例)、结节状甲状腺肿(34例),年龄60～77岁。分析比较这些疾病中CT影像上的钙化形态及分布特点。结果 7例(53.8%)甲状腺癌钙化,不规则分布(细粒样钙化5例,结节状钙化2例),腺瘤5例钙化(22.7%),规则分布(弧形钙化3例,结节状钙化2例),结节状甲状腺肿钙化11例(29.4%),不规则散在分布(弧状钙化6例,结节状钙化5例)。甲状腺癌钙化率与其他组比较差异有统计学意义(P<0.05),细粒样钙化和弧形钙化在良、恶性结节中出现率差异有统计学意义(P<0.05)。结论在老年甲状腺结节患者中,甲状腺癌钙化率最高,以细粒状钙化中心和偏中心分布为主;弧形钙化出现在良性的结节状甲状腺肿和腺瘤中,偏心或边缘分布。3种甲状腺结节中均可出现结节状钙化,无诊断特异性。更多还原

【Abstract】 Objective To discuss the characteristics of thyroid nodule calcification in the elderly and the morphology and distribution so as to improve the diagnostic accuracy of benign and malignant thyroid nodules. Methods A retrospective analysis was made to the imaging data of 69 cases with thyroid nodules confirmed by pathological study in the past 5 years, including 13 cases with thyroid cancer, 22 cases with adenoma, 34 cases with nodular goiter, the age of the cases was from 60 to 77 years old; the morphology and distribution characteristics of the diseases on CT images were analyzed. Results Irregular distribution of calcification was found in 7 cases with thyroid cancer(53.8%): fine-grained calcification in 5 cases and nodular calcification in 2 cases; regular distribution was found 5 cases with adenoma(22.7%): curvilinear calcification in 3 cases and nodular calcification in 2 cases; dotted irregular distribution was found in 11 cases with nodular goiters(NG) calcification(29.4%): curvilinear calcification in 6 cases and nodular calcification in 5 cases); there existed a statistical difference in calcification rate between thyroid cancer and other thyroid diseases(P<0.05) while a statistical difference in detection rate of benign and malignant thyroid nodules between fine-grained calcification and curvilinear calcification. Conclusions Thyroid cancer is of the highest calcification rate in the elderly with thyroid nodules, mainly fine-grained calcifications with central or eccentric distribution; curvilinear calcification are found in benign thyroid nodules and adenoma with in eccentric or marginal distribution;the 3 thyroid nodules may have calcification, which indicates no specificity in diagnosis.更多还原