【摘要】 目的探讨黄浦区社区老年高血压人群同型半胱氨酸(HCY)升高的流行现状及其心脑血管疾病风险。方法采用简单随机抽样方法,在黄浦区社区高血压患者管理系统中抽取1 160例,年龄≥60岁的原发性高血压患者进行患病情况问卷调查和相关指标检测,采用描述性流行病学方法分析H型高血压患病情况及该人群心脑血管疾病危险因素聚集暴露情况。结果有效调查1 082例,检出H型高血压904例,检出率为83.5%。男性患病率为87.0%,高于女性的79.9%(P<0.05);患病率随着年龄增长而呈升高趋势(P<0.05)。Logistic回归提示糖尿病、吸烟、饮酒及肥胖更可能导致HCY的升高(P<0.05)。H型高血压患者比单纯高血压患者有更高的心脑血管疾病危险因素聚集(具有≥3项心脑血管疾病危险因素)暴露率(P<0.05);男性患者的平均暴露个数高于女性(P<0.05)。结论黄浦区老年H型高血压患病率高,心脑血管疾病危险因素聚集差异显著,应针对H型高血压患者开展个性化的社区慢性病健康教育,改变患者的生活行为模式,降低心脑血管疾病风险,提高其生活质量。更多还原

【Abstract】 Objective To investigate the epidemiological status of increased homocysteine(HCY) in the elderly with hypertension in the community of Huangpu District, Shanghai and to analyze the risks of cardio-cerebrovascular diseases. Methods 1160 cases were randomly selected from hypertension database;questionnaire and related detections were made to the cases with primary hypertension, aged ≥60 years; the method of descriptive epidemiology was applied in analyzing the prevalence of H-type hypertension and the risks of cardio-cerebrovascular diseases. Results The investigation of 1082 cases was valid;H-type hypertension was detected out in 904 cases with the detection rate of 83.5%;the morbidity rate in male was 87.0%,higher than that in female(79.9%)(P<0.05);the morbidity rate increased with the age going(P<0.05);Logistic Regression Analysis indicated that diabetes,smoking,drinking and obesity might lead to the raise of HCY(P<0.05);cases with H-type hypertension were of higher exposure rate to more risk factors of cardio-cerebrovascular diseases(≥3 risk factors) than the cases with simple hypertension and the average risk factors of exposure in male were more than those in female. Conclusions The morbidity of H-type hypertension in the elderly is high in the community of Huangpu District,Shanghai and the cardio-cerebrovascular risk factors clustering is of obvious differences;specific community health education targeted on H-type hypertension should be provided so as to change the living behavior model of the cases,reduce the risk of cardio-cerebrovascular diseases and promote the quality of life.更多还原