【摘要】 目的探讨青岛市立医院腹腔镜胆囊切除术围术期抗菌药物的应用情况。方法选取本院2018年1月至2018年12月行腹腔镜下胆囊切除术的患者93例,分析其抗菌药物使用类别,抗菌药物用药频度(defined daily doses, DDDs),药物联用情况,抗菌药物使用时长等。结果行腹腔镜胆囊切除术(laparoscopic cholecystectomy, LC)患者围术期抗菌药物使用情况,抗菌药物DDDs使用排名第一的为左奥硝唑,但都为与其他药物联用。排名第二的为头孢唑林钠。抗菌药物单一使用率为51.6%,多为头孢菌素类,以一、二代头孢为主;有47.3%的患者在头孢菌素的基础上加用了硝基咪唑类;抗菌药物平均使用时长(4.3±0.78)d。结论行LC患者围术期抗菌药物使用基本合理,但也存在一些用药不合理现象,如用药日剂量过大,用药时间过长。更多还原

【Abstract】 Objective To discuss the application of the antimicrobial drugs during perioperative period of laparoscopic cholecystectomy(LC) in Qingdao Municipal Hospital. Methods From January2018 to December 2018, 93 patients who undertook LC were selected. The drug types, defined daily doses(DDDs), use duration of the antibiotics and combination use of drugs were analyzed respectively.Result S-ornidazole was used most and had the highest DDDs value. But it was all used in combination with other drugs. And the second is cefazolin sodium. 51.6% patients used one antimicrobial drug and mostly used the first and second generation of cepha-losporins. 47.3% patients used one cephalosporin combined with S-ornidazole. The average use duration of antimicrobial drugs is(4.3±0.78)days.Conclusion The application of antimicrobial drugs was basically rational. But there was still some unreasonable use such as high daily doses and long duration of drugs.更多还原