【摘要】 报告1例溃疡性结肠炎并发坏疽性脓皮病。患者女,41岁。间断黏液脓血便13年,加重伴皮肤溃疡20 d。皮肤科检查:颈部右侧、右前胸壁、右腰部大片红色斑丘疹,中间有溃疡形成,见大量脓液。皮损组织病理检查:真皮全层纤维母细胞增生,胶原间见较多上皮样细胞及白细胞,并可见多核巨细胞,局部见微脓肿,血管周围见白细胞浸润。诊断:坏疽性脓皮病。更多还原

【Abstract】 We report a case of gangrenous pyoderma complicated with ulcerative colitis. A 41 years old woman presented with intermittent purulent-bloody stool for 13 years and aggravated with painful cutaneous ulcers for 20 days. Physical examination showed painful ulcers with a lot of pus on large maculopapules on the right side of the neck, chest and waist.Histopathologic examination showed fibroblast proliferation in the dermis, abundant epithelioid cells and leukocytes, and some multinucleated giant cells in the collagen layer, with microabscess and perivascular leukocytic infiltrates. The patient was diagnosed with gangrenous pyoderma complicated with ulcerative colitis.更多还原