【摘要】 目的:探讨口底腺源性肿瘤的临床特点、治疗方式及预后。方法:对37例口底腺源性肿瘤患者临床资料进行回顾分析,评估其临床特点、治疗方式及预后。结果:37例口底腺源性肿瘤中恶性肿瘤33例,良性肿瘤4例。男女比为0.76:1。40～60岁患者占54.1%。舌麻木及前伸运动受限、颌骨受累者仅见于恶性肿瘤。81.8%的恶性肿瘤患者在切除原发灶时同期行颈淋巴清扫术,术后病检结果淋巴结转移率为29.6%。在随访时间超过3年的16例恶性肿瘤患者中,局部复发者4例,伴有舌活动受限者3年总体生存率显著减低(P=0.009)。4例良性肿瘤术后均无复发。结论:口底腺源性肿瘤以恶性居多,发生舌活动受限是影响预后的重要因素。更多还原

【Abstract】 Objective:To explore the clinical features,treatment methods and prognosis of salivary tumors of the floor of the mouth.Methods:A retrospective study was performed on salivary tumors of the floor of the mouth by assessing clinical features,treatment and prognosis of 37 patients.Results:There were 33 cases of malignant tumors and 4 cases of benign tumors.The ratio of male to female was 0.76.Patients between 40 and 60 years old accounted for 54.1% of all.Numbness and limited mobility of the tongue,and bone destruction only occurred in malignant tumor patients.There were 81.8% of malignant tumor patients undergoing neck dissection,of which 29.6% had metastasis of lymph nodes.Among 16 patients,who were followed up for more than 3 years,4 patients had local recurrence.And 3-year overall survival rate was significantly lower in patients with limited mobility of the tongue(P=0.009).The 4 cases of benign tumors had no signs of recurrence after operation.Conclusion:Salivary tumors of the floor of the mouth are mostly malignant,and the limited mobility of the tongue is an important factor affecting prognosis of these patients.更多还原