【摘要】 [目的]研究高血压脑出血血肿清除术后应用银杏叶提取物的疗效及不良反应发生率。[方法]选取2015年1月至2017年9月收住于河南大学淮河医院神经外科及开封市中医院神经外科的高血压脑出血患者共120例,按随机表法分为对照组和治疗组(各60例)。对照组行血肿清除术后予以常规对症支持治疗,治疗组在对照组治疗基础上于术后7 d应用银杏叶提取物治疗14 d。术后6 mon对患者进行美国国立卫生研究院卒中量表(National Institute of Health stroke scale,NIHSS)评分、Barthel指数(the Barthelindex of ADL)评分,格拉斯哥预后评分(Glasgow Outcome Scale,GOS)。[结果]治疗组NIHSS评分、Barthel指数及GOS评分均优于对照组(P <0.05)。[结论]高血压脑出血血肿清除术后患者应用银杏叶提取物安全有效,同时可显著改善预后。更多还原

【Abstract】 [Objective]To study the clinical efficacy and the rate of adverse reaction of ginkgo biloba leaf extract in the treatment of hypertensive cerebral hemorrhage( HICH) after invasive evacuation of hematoma. [Methods]From January 2015 to September2017, 120 patients with HICH were diagnosed at the department of neurosurgery in Huaihe Hospital of Henan University and the department of neurosurgery in Kaifeng Hospital of Traditional Chinese Medicine and randomly assigned into the control group and the treatment group. The control group was treated with conventional symptomatic treatment after invasive evacuation of hematoma, while the treatment group was treated with ginkgo biloba leaf extract for 14 days on the basis of the control group after operation. Six months after operation, the effects were observed and the National Institute of Health stroke scale( NIHSS), the Barthelindex of ADL and Glasgow Outcome Scale( GOS) scores were evaluated in the patients.[Results]After the treatment, the levels of NIHSS, Barthelindex of ADL and GOS scores in the treatment group were significantly improved than the control group( P < 0.05).[Conclusion]Ginkgo biloba leaf extract has better clinical efficacy and safety, and can significantly improve the prognosis of the patients in the treatment of HICH after invasive evacuation of hematoma.更多还原