【摘要】 冲动控制障碍(ICD)是在帕金森病患者诊治过程中需要关注的并发症,在使用多巴胺受体激动剂治疗后ICD发生率明显增加。帕金森病患者合并ICD,可能机制为中脑-纹状体-边缘系统-皮质区的纤维联系改变。多巴胺能药物治疗、性别、吸烟、多巴胺转运体的减少与ICD的发生可能相关。现就帕金森病中的ICD相关研究作一综述。更多还原

【Abstract】 Impulse control disorder(ICD) is a complication in Pakinson disease requiring attention.There is a significant increase in the incidence of ICD after using dopamine agonists.In Parkinson disease patients with ICD,there are corresponding changes of fiber connections in the midbrain-striatum-limbic systemcortex.The occurrence of ICD in Parkinson disease is related to dopaminergic drug therapy,gender,smoking and the decrease of dopamine transporter.This review summarizes the relevant findings concerning ICD in Parkison disease.更多还原