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NLRP3炎性小体在蛛网膜下腔出血中的研究进展
Research progress of NLRP3 inflammasome in subarachnoid hemorrhage
【摘要】 蛛网膜下腔出血(SAH)是一种急性脑血管疾病,近年来炎性反应被认为在SAH及其并发症中起着重要作用,而NLRP3炎性小体在炎性反应中起关键作用,但其具体作用机制有待进一步阐明。现针对NLRP3炎性小体在SAH中的作用及相关研究作一综述,旨在为SAH的临床研究和治疗策略提供相关线索。
【Abstract】 Subarachnoid hemorrhage(SAH)is an acute cerebrovascular disease.In recent years,inflammatory responses have been considered to play an important role in SAH and its complications.The NLRP3 inflammasome plays a key role in the inflammatory response with its mechanism yet to be specified.This review focuses on the role and related research of NLRP3 inflammasome in SAH,aiming to provide references for clinical studies and treatment strategies of SAH.
【关键词】 蛛网膜下腔出血;
NLRP3炎性小体;
炎性反应;
【Key words】 Subarachnoid hemorrhage; NLRP3 inflammasome; Inflammation;
【Key words】 Subarachnoid hemorrhage; NLRP3 inflammasome; Inflammation;
【基金】 川北医学院校级科研发展计划项目(CBY17-A-ZD09)~~
- 【文献出处】 神经疾病与精神卫生 ,Journal of Neuroscience and Mental Health , 编辑部邮箱 ,2019年06期
- 【分类号】R743.35