【摘要】 目的分析甘肃省丙型肝炎(丙肝)的流行特征及规律,为进一步控制丙肝疫情提供参考信息。方法采用描述流行病学方法,分析2008-2017年甘肃省丙肝病例流行病学特征,采用SPSS 20.0软件进行统计分析,率的比较采用χ~2检验。结果共报告丙肝病例72 899例,发病总体呈上升趋势(χ~2=1 330.472, P<0.01),2012年丙肝报告发病率达到高峰,为34.93/10万;男女性比为1.08～1.83∶1。20～49岁年龄组累计报告病例数占42.94%,并逐年下降;≥50岁年龄组病例报告发病率总体呈上升趋势(χ~2=1 342.154,P<0.05),且女性报告病例数所占比例呈上升趋势;农民35 919例,占49.27%,且病例数逐年上升;全年各月均有发病,发病率在1/10万～3/10万波动;兰州、武威市丙肝发病率高于其他地区。结论甘肃省丙肝发病率总体呈上升趋势,无明显季节性波动,地区分布差异有统计学意义,发病率随年龄增加呈上升趋势,需加强对重点人群和地区的疫情监测。更多还原

【Abstract】 Objective To analyzed the epidemiological characteristics of hepatitis C in Gansu province and provide scientific evidence for the improvement of prevention and control of hepatitis C. Methods The incidence data of hepatitis C in Gansu from 2008 to 2017 were collected for a descriptive epidemiological analysis. The statistical analysis was done with software SPSS 20.0 and the rate comparison was through χ~2 test Results A total of 72 899 cases of hepatitis C were reported in Gansu during this period. The incidence rate of hepatitis C showed an increase trend from 20.92/100 000 to 29.71/100 000(χ~2=1 330.472, P<0.01) and reached peak of 34.93/100 000 in 2012. The male to female ratios of the cases were 1.08∶ 1 and1.83∶ 1 respectively. The cumulative case number in age group 20–49 years accounted for 42.94% of the total, showing a decrease trend. The reported incidence rate in age group ≥50 years increased year by year(χ~2=1 342.154,P<0.05), The proportion of the cases reported in women showed an increase trend. The cases in farmers accounted for 49.27%(35 919 cases)and increased with year. Hepatitis C occurred all the year round. The incidence rates ranged from 1/100 000 to 3/100 000. The incidence rates of hepatitis C in Wuwei and Lanzhou were higher than those in other areas. Conclusion The overall incidence of hepatitis C in Gansu was in increase without obvious seasonality. The difference in incidences among different areas was significant, and the incidence rate increased with age. It is necessary to strengthen the surveillance for hepatitis C in key populations and areas.更多还原