【摘要】 目的分析单操作孔胸腔镜下T₃胸交感神经链切断术治疗手汗症的临床效果。方法便利抽取2018年1月—2019年1月该院收治的40例手汗症患者作为研究对象,回顾所有患者病例资料,根据不同的治疗方案作为分组依据,将40例患者分为对照组、实验组,每组20例。对照组用双孔胸腔镜治疗,实验组用单操作孔胸腔镜下T₃胸交感神经链切断术治疗,对比两组手术观察指标、疼痛程度、C反应蛋白、白介素-6、皮质醇、临床症状评分。结果实验组手术切口长度（12.77±1.59）mm、手术时间（30.24±2.47）min、术中出血量（10.74±2.09）mL、住院时间（1.25±0.87）d短于对照组,差异有统计学意义（t=5.411、3.567、5.065、3.823,P<0.05）;实验组术后2、12、24 h疼痛程度[（4.36±0.88）分、（3.34±0.57）分、（1.47±0.35）分]、C反应蛋白（3.03±0.80）mg/L、白介素-6（14.29±2.45）pg/m L、皮质醇（129.21±26.01）ng/mL、临床症状评分（3.88±1.06）分低于对照组,差异有统计学意义（t=4.049、3.851、5.616,P<0.05;t=4.339、4.825、4.650、3.752,P<0.05）。结论单操作孔胸腔镜下T₃胸交感神经链切断术治疗手汗症,不仅可以改善手术观察指标,还可以降低C反应蛋白、白介素-6、皮质醇水平,缓解临床症状,治疗效果显著,值得临床推广应用。更多还原

【Abstract】 Objective To analyze the clinical effect of T₃ thoracic sympathectomy with thoracoscopic surgery for hand sweating. Methods Convenient selected 40 patients with hand sweat admitted to our hospital from January 2018 to January 2019 were enrolled. All patients were reviewed. According to different treatment plans, 40 patients were divided into control group and experimental group, 20 cases in each group. The control group was treated with double-hole thoracoscopic surgery. The experimental group was treated with T₃ thoracic sympathectomy with single-operated hole. The surgical observation index, pain level, C-reactive protein, interleukin-6, cortisol, and clinical symptoms were compared between the two groups. Results The length of surgical incision（12.77±1.59） mm, operation time（30.24±2.47） min, intraoperative blood loss（10.74±2.09） mL, and hospitalization time（1.25±0.87） d were shorter than the control group. The difference was statistically significant（t=5.411, 3.567, 5.065, 3.823, P<0.05）; pain degree at 2, 12, 24 h after operation in the experimental group[（4.36±0.88）points,（3.34±0.57）points,（1.47±0.35）points] C-reactive protein（3.03±0.80） mg/L, interleukin-6（14.29±2.45）pg/mL,cortisol（129.21±26.01） ng/mL, and clinical symptom score（3.88±1.06）points were lower than the control group. The difference was statistically significant（t=4.049, 3.851, 5.616, P<0.05; t=4.339, 4.825, 4.650, 3.752, P<0.05）. Conclusion T₃ thoracic sympathectomy for thoracic surgery with single-operated hole can not only improve the surgical observation index,but also reduce C-reactive protein, interleukin-6, cortisol levels, relieve clinical symptoms, and the treatment effect is remarkablem, with clinical application value.更多还原