【摘要】 脓毒症(sepsis)是机体对感染反应失调从而导致了危及生命的器官功能障碍,是感染性疾病重要的死亡原因。目前关于脓毒症的早期诊断、预后判断的生物标记物研究有数百种,但各有弊端。近年发现一种新的标记物,即Presepsin(可溶性CD14分子亚型,s CD14-T),其在脓毒症诊断与评价的研究中显示了良好的临床意义。现就Presepsin本身及其在脓毒症诊断中的意义做一综述。更多还原

【Abstract】 Sepsis is a disorder of the body’s response to infection, which leads to life-threatening organ dysfunction and is an important cause of death in infectious diseases. There are hundreds of biomarker studies on the early diagnosis and prognosis of sepsis, but each has its drawbacks. In recent years, a new marker, Presepsin(soluble CD14 molecular subtype,sCD14-T), has been found to show good clinical significance in the study of sepsis diagnosis and evaluation. This article reviews the significance of Presepsin itself and its diagnosis in sepsis.更多还原