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快速心律失常采用胺碘酮与美托洛尔静脉注射联用的疗效探讨
Efficacy of Amiodarone Combined with Metoprolol Intravenous Injection for Tachyarrhythmia
【摘要】 目的分析胺碘酮治疗冠心病急性心肌梗死伴高危快速型心律失常的临床效果。方法在2017年10月—2018年10月开展本次关于快速心律失常的治疗研究,期间总共方便选取60例患者作为案例进行对比分析。以掷骰子方式将所选患者进行分组。两组患者均在研究期间保持卧床静养,常规组采取美托洛尔进行治疗,实验组在常规组基础上采用胺碘酮。总结两组患者临床疗效。结果治疗后,常规组有效率为80.00%,低于实验组的96.67%,两组比较差异具有统计学意义(χ~2=12.546,P=0.023);治疗前两组患者的心率、血压指标差异不突出,对比结果无意义(心率、SBP、DBP对比结果(t=2.013、2.314、2.001,P=0.067、0.078、0.057);治疗后实验组患者的心率、血压指标优势突出,数据差异较大,对比结果有意义(心率、SBP、DBP对比结果(t=6.774、6.159、7.056,P=0.023、0.021、0.013)。结论胺碘酮治疗冠心病急性心肌梗死伴高危快速型心律失常的临床效果显著,能够有效的改善患者的脏器功能,优化心脏功能,改善预后效果,值得在临床中推广。
【Abstract】 Objective To analyze the clinical effect of amiodarone in the treatment of acute myocardial infarction with highrisk tachyarrhythmia. Methods From October 2017 to October 2018, the research on the treatment of tachyarrhythmia was carried out. A total of 60 patients were convenient selected as cases for comparative analysis. The patients were divided into groups by dice throwing. Two groups of patients were kept in bed during the study period, the conventional group was treated with metoprolol, and the experimental group was treated with amiodarone on the basis of the conventional group. The clinical efficacy and medication safety of the two groups were summarized. Results After treatment, the effective rate of the routine group was 80.00%, which was lower than that of the experimental group(96.67%). There was a significant difference between the two groups(χ~2=12.546,P=0.023). Before treatment, there was no significant difference in heart rate and blood pressure between the two groups, and the comparison results were meaningless(heart rate, SBP, DBP, t=2.013, 2.314, 2.001 P =0.067, 0.078, 0.057). The blood pressure indicators have prominent advantages, and the data are quite different. The comparison results are meaningful(heart rate, SBP, DBP,t=6.774, 6.159, 7.056 P=0.023, 0.021, 0.013). Conclusion Amiodarone has a significant clinical effect in the treatment of acute myocardial infarction with high-risk tachyarrhythmia. It can effectively improve the organ function, optimize the heart function and improve the prognosis of patients with coronary heart disease. It is worth popularizing in clinical practice.
【Key words】 Amiodarone; Metoprolol; Tachyarrhythmia; Clinical efficacy;
- 【文献出处】 中外医疗 ,China & Foreign Medical Treatment , 编辑部邮箱 ,2019年13期
- 【分类号】R541.7
- 【被引频次】3
- 【下载频次】19