【摘要】 目的探讨替加环素联合头孢哌酮舒巴坦钠治疗广泛耐药鲍曼不动杆菌老年肺部感染效果。方法方便选取该院2017年4月—2018年4月收治的广泛耐药鲍曼不动杆菌老年肺部感染患者90例,随机分为两组,对照组采取头孢哌酮舒巴坦钠进行治疗,研究组采取替加环素联合头孢哌酮舒巴坦钠的方法进行治疗。结果对照组治疗有效率为46.5%,研究组治疗有效率为79.9%,研究组治疗效果明显优于对照组,差异有统计学意义(χ2=5.347,P<0.05),对照组清除率为13.3%,研究组有效率为42.2%,研究组广泛耐药鲍曼不动杆菌清除率高于对照组,差异有统计学意义(χ2=5.546,P<0.05)。结论在治疗多重耐药鲍曼不动杆菌肺炎的过程中,头孢哌酮舒巴坦钠联合替加环素进行治疗疗效好,效果较为理想,临床上应当进一步推广应用。更多还原

【Abstract】 Objective To investigate the effect of tigecycline combined with cefoperazone sulbactam in the treatment of elderly patients with lung infection with Acinetobacter baumannii. Methods A total of 90 elderly patients with lung-infected Acinetobacter baumannii who were admitted to the hospital from April 2017 to April 2018 were convenient selected and randomly divided into two groups. The control group was treated with cefoperazone and sulbactam sodium. The study group was treated with tigecycline combined with cefoperazone sulbactam sodium. Results The effective rate of the control group was 46.5%, and the effective rate of the study group was 79.9%. The treatment effect of the study group was significantly better than that of the control group,the different was statistically significant(χ2=5.347, P<0.05), and the clearance rate of the control group was 13.3% and 42.2% of the study group, the clearance rate of extensive drug-resistant Acinetobacter baumannii in the study group was higher than that in the control group(χ2=5.546, P<0.05). Conclusion In the treatment of multi-drug resistant Acinetobacter baumannii pneumonia, cefoperazone sulbactam sodium combined with tigecycline is effective, and should be further promoted and applied clinically.更多还原