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血同型半胱氨酸与动脉硬化型缺血性脑卒中的相关性研究

Correlation Research of the Hcy Levels with Arteriosclerosis-associated Cerebral Ischemic Stroke

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【作者】 谢宁芳

【Author】 XIE Ning-fang;Department of Laboratory, Changge City People’s Hospital;

【通讯作者】 谢宁芳;

【机构】 河南省许昌市长葛市人民医院检验科

【摘要】 目的研究血同型半胱氨酸(Hcy)与动脉硬化型缺血性脑卒中的关系。方法临床纳入58例我院2014年3月至2017年3月期间收治的动脉硬化型缺血性脑卒中患者作为观察组,另纳入同期来我院体检中心进行体检的58例健康志愿者作为对照组。分别对两组对象进行血Hcy、空腹血糖(FBG)以及血脂等水平检测,观察血Hcy与动脉硬化型缺血性脑卒中的关系。结果观察组患者血Hcy水平明显高于对照组,P<0.05;而FBG、TC、TG、LDL-C以及HDL-C水平与对照组无差异,P>0.05。血Hcy与动脉硬化型缺血性脑卒中呈明显正相关,P<0.05;而其他指标(FBG、血脂各指标等)与动脉硬化型缺血性脑卒中无明显相关性,P>0.05。结论动脉硬化型缺血性脑卒中患者Hcy水平明显高于正常人群,血Hcy水平越高,患者病情越严重。

【Abstract】 Objective To study the correlation of the Hcy(homocysteine) level with arteriosclerosis-associated cerebral ischemic stroke. Methods 58 patients with arteriosclerosis-associated cerebral ischemic stroke treated from March 2014 to March 2017 in our hospital were selected(observation group). 58 healthy check-ups in our medical examination center were selected(control group). The index of Hcy, FBG and blood lipid for two groups were observed; the correlation of Hcy with the arteriosclerosis-associated cerebral ischemic stroke was analyzed. Results The index of Hcy for observation group was significantly higher than control group(P<0.05); the index of FBG, TC, TG, LDL-C and HDL-C for two groups were not significantly different(P>0.05), the index of Hcy had a close correlation with the arteriosclerosis-associated cerebral ischemic stroke(P<0.05); the other index(FBG, blood lipid, etc) had no obvious correlation with the arteriosclerosis-associated cerebral ischemic stroke(P>0.05). Conclusion The index of Hcy for arteriosclerosis-associated cerebral ischemic stroke patients is significantly higher than healthy group; the higher the Hcy level is, the more serious the illness condition is.

  • 【文献出处】 罕少疾病杂志 ,Journal of Rare and Uncommon Diseases , 编辑部邮箱 ,2019年03期
  • 【分类号】R743.3
  • 【被引频次】5
  • 【下载频次】75
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