【摘要】 目的探讨胸腺鳞癌的临床特征、诊治和预后。方法回顾性分析2013-05—2016-05间郑州大学第一附属医院经组织病理学确诊为胸腺鳞癌的49例患者的临床资料,包括患者的临床特征、术前影像学检查、治疗方法以及预后。结果 32例患者行手术治疗,余17例患者由于肿瘤无法切除采取化疗、放疗或放化疗的综合治疗。其间16例患者因肿瘤进展死亡,余33例患者均在定期随访中,3 a生存率为85.7%。结论胸腺鳞癌恶性程度高、预后差。手术是首选治疗方式,术后放疗、化疗或放化疗可能延长肿瘤复发时间,从而提高患者的生存率。更多还原

【Abstract】 Objective To explore the clinical features, diagnosis, treatment and prognosis of thymic squamous cell carcinoma.Methods A retrospective review of the medical records of 49 patients with thymic squamous cell carcinoma was conducted at the First Affiliated Hospital of Zhengzhou University between May 2013 and May 2016. The clinical characteristics, preoperative imaging, therapy and prognosis were analyzed.Results Surgery resection was performed in thirty-two patients. Due to the tumor could not be removed, the remaining 17 patients were treated with chemotherapy, radiotherapy or radiotherapy combined with chemotherapy. Till May 2019, 16 patients died for tumor progression, the remaining 33 patients were on regular follow-up. The survival rates after three years were 85.7%, respectively.Conclusion Thymic squamous cell carcinoma is highly malignant tumor with poor prognosis. Surgery resection is preferred treatment for thymic squamous cell carcinoma, postoperative chemotherapy, radiotherapy or radiotherapy combined with chemotherapy could prolong the tumor recurrence time and improve the survival rate of the patients.更多还原