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脾多肽注射液联合头孢哌酮钠他唑巴坦钠治疗对大叶性肺炎免疫功能影响及临床疗效研究

Effect of Splenic Polypeptide Injection Combined with Cefoperazone Sodium and Tazobactam Sodium on Immune Function and Clinical Efficacy of Lobular Pneumonia

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【作者】 杨晶王艳坤陈松柏

【Author】 YANG Jing;WANG Yankun;CHEN Songbai;Department of Pediatrics,The 242 Hospital of Harbin;

【机构】 航空工业哈尔滨二四二医院

【摘要】 目的观察并分析脾多肽注射液联合头孢哌酮钠他唑巴坦钠治疗对小儿大叶性肺炎免疫功能影响及临床疗效。方法将临床上确诊的小儿大叶性肺炎102例患儿随机分成两组,每组各51例,根据治疗方式不同分成对照组和观察组。对照组给予头孢哌酮钠他唑巴坦钠静点等常规抗感染对症治疗,观察组在对照组常规治疗的基础上加用脾多肽注射液。比较两组临床治疗效果及免疫功能变化情况。结果观察组患儿的总有效率显著高于对照组(P <0. 05),免疫功能(免疫球蛋白Ig A,Ig M,Ig G的水平)均显著提升(P <0. 05)。结论在常规治疗的基础上加用脾多肽治疗小儿大叶性肺炎,能显著提升临床疗效,改善患儿的免疫功能。

【Abstract】 Objective To observe and analyze the effect of splenic polypeptide injection combined with cefoperazone sodium and tazobactam sodium on immune function of lobular pneumonia and its clinical effect. Methods 102 cases of pediatric lobular pneumonia were randomly divided into 2 groups,51 cases in each group,and divided into control group and observation group according to different treatment methods. The control group was treated with cefoperazone sodium,tazobactam sodium and other conventional antiinfective symptomatic therapy,and the observation group was treated with splenic polypeptide injection on the basis of routine treatment in the control group. The clinical therapeutic effect and immune function of the two groups were compared. Results The total effective rate of the observation group was significantly higher than that of the control group( P < 0. 05),and the immune function( Ig A,Ig M,Ig G level) was significantly improved( P < 0. 05). Conclusions On the basis of routine treatment,splenic polypeptides in the treatment of pediatric lobar pneumonia can significantly improve the clinical efficacy and improve the immune function of children.

  • 【文献出处】 航空航天医学杂志 ,Journal of Aerospace Medicine , 编辑部邮箱 ,2019年06期
  • 【分类号】R725.6
  • 【被引频次】2
  • 【下载频次】58
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