【摘要】 目的:观察Intertan静力固定辅助钙尔奇D治疗骨质疏松性股骨粗隆间骨折的临床治疗效果。方法:从2013年3月至2017年1月骨质疏松性股骨粗隆间骨折患者中选取92例作为研究对象,随机分为两组,对照组给予PFNA手术联合钙尔奇D治疗,研究组给予Intertan静力固定辅助钙尔奇D治疗,每组各46例。观察对比两组髋关节功能、手术时间、术中出血量、骨性愈合时间、骨痛评分、骨密度(BMD)各项指标、骨代谢标志物以及血清骨硬化蛋白(SO)。结果:两组术后6个月Harris评分均显著高于术后1个月,且术后1个月与术后6个月研究组Harris评分均显著高于对照组(P<0.05);研究组手术时间、术中出血量、骨性愈合时间均显著低于对照组(P<0.05);两组治疗后骨痛评分均显著低于治疗前(P<0.05),且研究组骨痛评分显著低于对照组(P<0.05),治疗1年后两组BMD各项指标均显著高于治疗前(P<0.05),且研究组BMD各项指标显著优于对照组(P <0.05);治疗3个月后两组血清TRAP5b、β-CTX及SO水平显著低于治疗前(P <0.05),且组间比较差异具有统计学意义(P <0.05);两组血清T-PINP、N-MID水平显著高于治疗前(P <0.05),且组间比较差异具有统计学意义(P <0.05)。结论:Intertan静力固定辅助钙尔奇D治疗骨质疏松性股骨粗隆间骨折,疗效显著,可有效促进髋关节功能恢复,促进术后骨折愈合。更多还原

【Abstract】 Objective: To observe the clinical effect of intertan static fixation assisted with caltrate D in the treatment of osteoporotic femoral intertrochanteric fracture. Methods: From March 2013 to January 2017,92 cases of patients with osteoporotic femoral intertrochanteric fracture were selected and randomly divided into two groups,the control group was treated with PFNA operation combined with calcium D,and the study group was given Intertan static fixation assisted with Caltrate D,with 46 patients in each group. The two groups of hip joint function,operation time,amount of intraoperative bleeding,bone healing time,bone pain score,various indexes of bone density(BMD),bone metabolism markers,and serum bone sclerosis protein(SO) were compared. Results: The Harris scores in the two groups at 6 months after the operation were significantly higher than those at 1 month after the operation,and the Harris scores of the study group at 1 month and 6 months after the operation were significantly higher than those of the control group(P <0.05). The operative time,intraoperative blood loss and bone healing time in the study group were significantly lower than those in the control group(P <0.05). The bone pain scores in the two groups after treatment were significantly lower than those before treatment(P <0.05),and the bone pain score in the study group was significantly lower than that in the control group(P <0.05). After 1 year of treatment,the indexes of BMD in the two groups were significantly higher than those before treatment(P <0.05),and the indexes of BMD in the study group were significantly better than those in the control group(P <0.05). After treatment for 3 months,the levels of serum TRAP5 b,β-CTX and SO in the two groups were significantly lower than those before treatment(P <0.05),and the differences between the two groups were statistically significant(P <0.05). The serum T-PINP and N-MID levels in the two groups were significantly higher than those before treatment(P <0.05),and the differences between the two groups were statistically significant(P < 0.05). Conclusion: Intertan static fixation assisted with Caltrate D in the treatment of osteoporotic femoral intertrochanteric fracture is effective. It can effectively promote the recovery of hip joint function and promote postoperative fracture healing.更多还原