【摘要】 目的观察中西医结合治疗中心性浆液性脉络膜视网膜炎临床疗效。方法选取2017年1月至2018年1月在我院就诊的81例92眼中心性浆液性脉络膜视网膜炎(CSC)患者作为研究对象,所有患者按照就诊时间编号,单号设为对照组(41例46眼),双号设为观察组(40例46眼)。两组患者均采用常规西药维生素B、维生素C、肌苷片、地巴唑、脑络通治疗,观察组在对照组治疗基础上加用复明地黄汤加减治疗。所有患者均连续治疗30 d。治疗前及治疗后10 d、20 d、30 d分别检测患者视力和眼底,比较两组患者视力、眼底改善情况及平均改善时间,完成治疗后比较两组患者临床总有效率。收集两组患者治疗过程中药物不良反应率并比较。结果完成治疗后,观察组患者视力、眼底改善率比较差异无统计学意义(P>0.05),且观察组患者视力、眼底改善时间明显短于对照组,差异有统计学意义(P<0.05)。完成治疗后两组患者临床总有效率比较差异无统计学意义(P>0.05)。两组患者治疗期间均未发生严重药物不良反应。结论中西医结合治疗CSC可快速改善患者视力、眼底渗出、水肿等临床症状且安全,具有较高的临床应用价值。更多还原

【Abstract】 Objective To observe the clinical efficacy of combined traditional Chinese and western medicine in the treatment of central serous chorioretinitis, and to provide a reference for the treatment scheme selection of such patients. Methods 81 cases of 92 eyes with cardiac serous chorioretinitis(CSC) admitted to our hospital from January 2017 to January 2018 were selected as the study subjects. All patients were assigned to the control group(41 cases with 46 eyes) and the observation group(40 cases with 46 eyes) according to the number of visit time. Patients in both groups were treated with conventional western medicine vitamin B, vitamin C, creatine tablets, dibazole and naoluotong, and the observation group was treated with fuming dihuang decoction on the basis of the treatment in the control group. All patients received continuous treatment for 30 days. Before treatment, 10 d, 20 d and 30 d after treatment, all the patients’ vision and fundus improvement were detected, and the visual acuity, fundus improvement and average improvement time of the two groups were compared. After treatment, the total clinical efficiency of the two groups was compared. The rates of adverse drug reactions in the two groups were collected and compared. Results After treatment, there were no statistical significantly differences in the rate of visual acuity and fundus improvement between the observation group and the control group(P>0.05), but the visual acuity and fundus improvement time of the observation group was significantly shorter than that of the control group(P<0.05). After the completion of treatment, there were no statistical significantly differences in the total clinical effective rate between the two groups(P>0.05). No serious adverse drug reactions were observed during treatment in either group. Conclusion All patients with CSC are self-limited. The treatment of CSC with the combination of traditional Chinese and western medicine can rapidly improve the patients’ visual acuity, fundus exudation, edema and other clinical symptoms, and quickly recover the patients’ condition, which is safe and of high clinical value.更多还原