【摘要】 目的探讨早产儿视网膜病变筛查结果及其高危因素。方法回顾性分析我院新生儿病区2013年1月～2017年12月收治的胎龄≤33周早产儿167例的筛查资料,记录早产儿性别、胎龄、体重、贫血情况、呼吸机应用情况、输血情况等资料,分析早产儿视网膜病变高危因素。结果筛查结果显示早产儿视网膜病变25例,其中1期病变8例,2期病变10例,3期病变7例,未发现4期和5期病变;早产儿视网膜病变组出生胎龄小于非视网膜病变组,视网膜病变组出生体重,多胎,黄疸,肺炎,吸氧,窒息,呼吸机应用占比,输血败血症发生率等低于非视网膜病变组,差异有统计学意义(P <0.05)。视网膜病变组持续性肺动脉高压高于非视网膜病变组,差异无统计学意义(P> 0.05);此外,Logistic回归分析表明,出生胎龄较小、出生体重较轻、贫血、败血症、呼吸机应用为早产儿视网膜病变的独立危险因素。结论早产儿视网膜病变与胎龄、体重、输血、呼吸机使用等因素相关,临床应注重筛查,综合分析上述因素做及时诊治,有效控制患儿病情,改善其视力,降低失明发生率。更多还原

【Abstract】 Objective To explore screening results and high risk factors of retinopathyof premature infants.Methods Screening data of 167 premature infants with gestational age less than 33 weeks who were admitted to the newborn ward of our hospital from January 2013 to December 2017 were retrospectively analyzed.The gender,gestational age,weight,anemia,ventilator application,blood transfusion and other data of premature infants were recorded to analyze high risk factors of retinopathy of premature infants. Results The screening results showed that there were 25 cases of retinopathy of premature infants,including 8 cases of stage 1,10 cases of stage 2 and 7 cases of stage 3.There was no stage 4 or 5 lesion.The gestational age of the retinopathy group was shorter than that of the non-retinopathy group.The birth weight,multiple births,jaundice,pneumonia,oxygen inhalation,asphyxia,proportion of ventilator application and incidence of transfusion sepsis of theretinopathy group were lower than non-retinopathy group.The difference was statistically significant(P < 0.05).The persistent pulmonary hypertension in the retinopathy group was higher than that in the non-retinopathy group.The difference was not statistically significant(P > 0.05).In addition,Logistic regression analysis showed that small gestational age,light birth weight,anemia,sepsis and ventilator application were independent risk factors for retinopathy of premature infants. Conclusion There tinopathy of premature infants is related to gestational age,weight,blood transfusion and ventilator application.Screening should be paid attention to in clinical practice.Comprehensive analysis of the above factors for timely diagnosis and treatment can effectively control the condition of premature infants,improve their vision and reduce the incidence of blindness.更多还原