【摘要】 目的了解苏州地区儿童血清25（OH）D₃的水平状态,为0～6岁儿童合理补充维生素D提供科学依据。方法选取苏州市立医院儿童保健门诊2015年9月至2016年9月常规体检的15 010例儿童,其中男7 905例,女7 105例,通过采集其指尖血进行血清25（OH）D₃检测。结果 （1）苏州地区15 010例0～6岁儿童血清25（OH）D₃均值为（35.83±13.23）μg/L,男、女童血清25（OH）D₃均值分别为（36.48±13.25）、（35.11±13.16）μg/L,差异有统计学意义（P<0.01）。（2）0～<3、3～<6、6～<12、12～<36、36～<48、≥48个月年龄段儿童血清25（OH）D₃均值分别为（34.49±11.53）、（41.15±13.86）、（48.03±17.25）、（46.12±17.69）、（28.49±16.55）和（42.28±17.59）μg/L,除3～<6个月年龄段儿童与≥48个月比较差异无统计学意义外,其余各年龄段两两比较差异均有统计学意义（P<0.05）。（3）1～12月检测的血清25（OH）D₃中除1、2、3月与11月,7月与8月两两比较差异无统计学意义外,其余各月份之间比较差异均有统计学意义（P<0.01）。按维生素D水平判断标准分级,各月份血清25（OH）D₃分级构成比差异有统计学意义（P<0.01）。25（OH）D₃>30μg/L比例低于50%的月份为1、3、11月,比例在50%～60%为2、6、12月,比例在60%～70%为7、8、9月,比例>70%的月份为4、5和10月。结论苏州地区学龄儿童血清25（OH）D₃水平下降明显,应加强宣教,关注该年龄段儿童维生素D的摄入情况。更多还原

【Abstract】 Objective To study the level of serum 25(OH)D3 in children in suzhou area,and to provide scientific basis for the rational supplement of vitamin D for children aged 0-6 years.Methods From September2015 to September 2016,15 010 children underwent routine physical examination in the Children′s Health Clinic of Suzhou Municipal Hospital were selected,of whom 7 905 were male and 7 105 were female.The serum 25(OH)D3 was detected by collecting their fingerling blood.Results(1)The mean serum 25(OH)D3 of15 010 children aged 0 to 6 in Suzhou was(35.83±13.23)μg/L,and the mean serum 25(OH)D3 of male and female were(36.48±13.25)and(35.11±13.16)μg/L respectively,and the differences were statistically significant(P<0.01).(2)The mean level of serum 25(OH)D3 of 0-<3,3-<6,6-<12,12-<36,36-<48 and≥48 months old children were(34.49±11.53),(41.15±13.86),(48.03±17.25),(46.12±17.69),(28.49±16.55)and(42.28±17.59)μg/L.The detection levels of serum 25(OH)D3 between the age groups were statistically significant(P<0.05)except the children 3-<6 months and≥48 months.(3)From January to December,the detection levels of serum 25(OH)D3 were statistically significant between different months(P<0.01)except in January,February,March and November,as well as July and August.The serum25(OH)D3 in each month was graded according to the vitamin D level,and the detection levels of serum 25(OH)D3 between different months were statistically significant(P<0.01).The proportion of serum 25(OH)D3 over 30μg/L was less than 50%in January,March and November.The ratio ranged from 50%to 60%in February,June and December.The ratio ranged from 60%to 70%in the July,August and September,while the proportion was over 70%in April,May and October.Conclusion The level of serum 25(OH)D3 in children in Suzhou area was decreased obviously,and health education should be strengthened,and attention should be paid to intaking of vitamin D in children.更多还原