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基于双向深度生成模型和功能磁共振成像数据的大脑编码和解码

Brain Encoding and Decoding in fMRI with Bidirectional Deep Generative Models

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【作者】 杜长德李劲鹏黄利皆何晖光

【Author】 Changde Du;Jinpeng Li;Lijie Huang;Huiguang He;Research Center for Brain-Inspired Intelligence and National Laboratory of Pattern Recognition, Institute of Automation, Chinese Academy of Sciences (CAS);School of Artificial Intelligence, University of Chinese Academy of Sciences;Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences;

【通讯作者】 何晖光;

【机构】 Research Center for Brain-Inspired Intelligence and National Laboratory of Pattern Recognition, Institute of Automation, Chinese Academy of Sciences (CAS)School of Artificial Intelligence, University of Chinese Academy of SciencesCenter for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences

【摘要】 通过功能磁共振成像(fMRI)进行大脑编码和解码是视觉神经科学的两个重要方面。尽管以前的研究人员在大脑编码和解码模型方面取得了显著进步,但是现有方法仍需要使用先进的机器学习技术进行改进。例如,传统方法通常会分别构建编码和解码模型,并且容易对小型数据集过度拟合。实际上,有效地统一编码和解码过程可以进行更准确的预测。在本文中,我们首先回顾了现有的编码和解码方法,并讨论了"双向"建模策略的潜在优势。接下来,在体系结构和计算规则方面,我们证明了深度神经网络和人类视觉通路之间存在的对应关系。此外,深度生成模型[如变分自编码器(VAE)和生成对抗网络(GAN)]在大脑编码和解码研究中产生了可喜的成果。最后,我们提出了最初为机器翻译任务设计的对偶学习方法,该方法通过利用大规模未配对数据提高了编码和解码模型的效果。

【Abstract】 Brain encoding and decoding via functional magnetic resonance imaging(fMRI) are two important aspects of visual perception neuroscience.Although previous researchers have made significant advances in brain encoding and decoding models,existing methods still require improvement using advanced machine learning techniques.For example,traditional methods usually build the encoding and decoding models separately,and are prone to overfitting on a small dataset.In fact,effectively unifying the encoding and decoding procedures may allow for more accurate predictions.In this paper,we first review the existing encoding and decoding methods and discuss the potential advantages of a "bidirectional" modeling strategy.Next,we show that there are correspondences between deep neural networks and human visual streams in terms of the architecture and computational rules.Furthermore,deep generative models(e.g.,variational autoencoders(VAEs) and generative adversarial networks(GANs)) have produced promising results in studies on brain encoding and decoding.Finally,we propose that the dual learning method,which was originally designed for machine translation tasks,could help to improve the performance of encoding and decoding models by leveraging large-scale unpaired data.

【基金】 国家重点研发计划(2018YFC2001302);国家自然科学基金(91520202);中国科学院科研装备研制项目(YJKYYQ20170050);中国科学院青年创新促进会和中国科学院战略性先导科技专项(XDB32040200)的支持;北京市科学技术委员会(Z181100008918010)~~
  • 【分类号】R445.2;TP391.41
  • 【被引频次】5
  • 【下载频次】117
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