节点文献
基于XGBoost的RNA修饰位点的识别
Identifying the occurrence sites of different RNA modifications based on XGBoost
【摘要】 为了实现用一种方法更准确地识别几种不同类型的RNA修饰位点,提出了一种融合位置特异性单核苷酸及双核苷酸偏好特征的k-元组核苷酸组成(PseKNC)编码方式,并构建了一个基于XGBoost的RNA修饰位点的预测模型。通过交叉验证测试表明,该模型的识别准确率优于现有模型。
【Abstract】 In order to identify several different types of RNA modification sites more accurately in one way,it proposes pseudo k-tuple nucleotide composition(PseKNC)encoding method that combines the position-specific mononucleotide and dinucleotide propensity characteristics.In addition,a new model for identifying RNA modification sites based on this encoding method is built.The cross-validation test shows that the recognition accuracy of this model is better than that of the existing model.
【关键词】 RNA;
修饰位点;
机器学习;
识别;
XGBoost;
【Key words】 RNA; modification sites; machine learning; identifying; XGBoost;
【Key words】 RNA; modification sites; machine learning; identifying; XGBoost;
【基金】 国家自然科学基金(61462018,61762026);广西自然科学基金(2017GXNSFAA198278);桂林电子科技大学研究生教育创新计划(2018YJCX47)
- 【文献出处】 桂林电子科技大学学报 ,Journal of Guilin University of Electronic Technology , 编辑部邮箱 ,2019年06期
- 【分类号】Q811.4
- 【下载频次】61