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基于三维卷积神经网络的肺结节假阳性筛查

False Positive Reduction of Pulmonary Nodules Using 3D CNN

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【作者】 尤堃郝鹏翼吴福理张繁吴健

【Author】 YOU Kun;HAO Peng-yi;WU Fu-li;ZHANG Fan;WU Jian;School of Computer Science and Technology, Zhejiang University of Technology;Real Doctor Artificial Intelligence Research Center, Zhejiang University;School of Computer Science and Technology, Zhejiang University;

【通讯作者】 郝鹏翼;

【机构】 浙江工业大学计算机科学与技术学院浙江大学睿医人工智能研究中心浙江大学计算机科学与技术学院

【摘要】 从CT影像中检测肺结节在肺癌的早期诊断中至关重要,而肺结节假阳性的筛查是提高肺结节检测准确度的重要一步。为了从大量候选结节中快速准确地区分出真正的肺结节,设计了一个3D卷积神经网络(CNN)筛查肺结节假阳性。提出了网络模型,通过恒等映射和残差单元来加速模型训练,采用单连接路径重复利用特征并重组新特征。基于该模型的肺结节假阳性筛查方法,与基于2D CNN的方法相比,不仅可以省略数据切片步骤,而且能够充分利用CT影像的空间信息;与其他基于3DCNN的方法相比,具有参数量小、模型训练快的优点。该方法在LUNA16数据集中的假阳性筛查中取得了较高的敏感度。

【Abstract】 Pulmonary Nodule Detection is the most promising way in early detection of pulmonary cancer.False positive reduction is one of the most crucial steps for improving the accuracy in automatic pulmonary nodule detection. For quickly and accurately discriminate true nodules from a large number of candidates, a 3 D convolutional neural networks(CNN) is proposed for false positive reduction. In the proposed network, identity mapping and residual unit are adopted to accelerate network training. At the same time, single connected path is explored to get new features. Compared with 2 D CNN based pulmonary nodule detection methods, the proposed method based on the proposed 3 D CNN can take full advantage of space structure of CT. Compared with other 3 D CNN based pulmonary nodule detection methods, the proposed method has fewer parameters that can make the training very fast. Experimental results on the public LUNA16 dataset demonstrate superior performance of the proposed method.

【关键词】 3D CNN肺结节假阳性筛查
【Key words】 3D CNNpulmonary nodulesfalse positive reduction
【基金】 国家自然科学基金项目(61801428,61672453);浙江省自然科学基金项目(LY18F020034);浙江大学教育基金会项目(K18-511120-004、K17-511120-017);之江实验室重大科研项目(2018DG0ZX01)
  • 【文献出处】 图学学报 ,Journal of Graphics , 编辑部邮箱 ,2019年03期
  • 【分类号】R563;TP391.41;TP183
  • 【被引频次】6
  • 【下载频次】249
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