【摘要】 目的:分析口服百草枯中毒患者肺损伤的胸部CT表现,探讨百草枯中毒患者CT征象与临床预后的关系。方法:回顾性分析78例口服百草枯中毒患者的临床及胸部CT影像资料,将78例患者根据预后分为生存组(40例)和死亡组(38例),分析两组百草枯中毒患者的胸部CT征象的差异,探讨影响临床预后的重要CT征象。结果:死亡组患者出现肺纹理增多、磨玻璃影、实变影、肺纤维化、肺过度充气等CT征象,以及纵隔/皮下气肿等并发症的比例高于生存组,差异有统计学意义(P<0.05);两组患者的肺部CT征象中,以肺纹理增多、胸膜下线、磨玻璃影等早期渗出性征象的诊断效能较高,曲线下面积(AUC)达0.87～0.93。结论:在口服百草枯中毒患者的胸部CT征象中,尤以磨玻璃影的范围及肺过度充气、纵隔/皮下气肿的有无与临床预后的关系最为密切,能为临床预后的判断提供重要的影像学依据。更多还原

【Abstract】 Objective:To investigate the correlation between chest CT findings and prognosis for patients with lung injury caused by paraquat.Methods:The clinical and chest CT data of seventy-eight patients with lung injury caused by oral paraquat were analyzed retrospectively.According to prognosis,the patients were divided into survival group(40 cases) and death group(38 cases).To compare the CT findings difference of 2 groups,and to determine the significant CT characteristics affecting clinical prognosis.Results: In death group,probability of CT characteristics such as increased lung texture,ground glass opacity,consolidation,pulmonary fibrosis,pulmonary hyperaeration and mediastinal/subcutaneous emphysema were more significant than those in survival group(P<0.05).The diagnostic efficiency of early exudation signs such as increased lung texture,subpleural line and ground glass opacity were high and the area under the curve(AUC) was 0.87～0.93.Conclusion:Chest CT findings in patients with oral paraquat,such as pulmonary hyperaeration,mediastinal/subcutaneous emphysema,and the range of ground glass opacity,are closely related to the clinical prognosis,which can provide important evidence for the prognostic estimation.更多还原