【摘要】 目的观察MRI联合四维超声在筛查胎儿心脏畸形中的应用价值。方法回顾性分析54例胎儿心脏畸形可疑病例临床资料,产前均行MRI及四维超声检查,根据出生后随访结果或尸检结果,分析MRI联合四维超声在筛查胎儿心脏畸形中的应用价值。结果 MRI联合四维超声诊断胎儿心脏畸形准确率显著高于各自单独诊断(P<0.05);MRI联合四维超声诊断胎儿心脏畸灵敏度、阴性预测值高于MRI单独诊断(P<0.05),但与四维超声诊断无显著差异(P>0.05);MRI、四维超声及二者联合诊断胎儿心脏畸形特异度、阳性预测值无显著性差异(P>0.05)。结论 MRI联合四维超声可提升对胎儿心脏畸形的诊断准确率,较各自单独诊断更具优势。更多还原

【Abstract】 Objective To observe the application value of MRI combined with fourdimensional ultrasound in the screening of fetal heart malformation. Methods The clinical data of 54 cases which suspected as fetal heart malformation were analyzed retrospectively.And they were given MRI and four-dimensional ultrasound examination before delivery.According to the results of postnatal follow-up or autopsy, the application value of MRI combined with four-dimensional ultrasound in the screening of fetal heart malformation was analyzed. Results The accuracy rate of MRI combined with four-dimensional ultrasound in the diagnosis of fetal heart malformation was significantly higher than that of single diagnosis(P<0.05). The sensitivity and negative predictive value of MRI combined with four-dimensional ultrasound in the diagnosis of fetal heart malformation were higher than those of MRI alone(P<0.05), but there were no significant differences compared with four-dimensional ultrasound(P>0.05). There were no significant differences in the specificity and positive predictive value of MRI, four-dimensional ultrasound and combination of the two in the diagnosis of fetal heart malformation(P>0.05). Conclusion MRI combined with four-dimensional ultrasound helps to improve the diagnostic accuracy rate of fetal heart malformation, and it is more advantageous than their respective diagnosis.更多还原