【摘要】 牙组织修复与再生一直是医学亟待解决的问题.采用氟基硅酸钙生物陶瓷材料对牙齿进行仿生矿化修复,在模拟仿生矿化液中,对酸蚀的牙齿进行处理,在釉原蛋白诱导下进行矿化,构建仿生牙组织结构.矿化层的性能表征结果显示,釉原蛋白诱导氟基硅酸钙能在牙釉质表面形成仿生矿化层,且较单一的氟基硅酸钙诱导形成磷灰石矿化层更加致密,力学性能更加优异,且晶粒有序排列,沿着一定方向定向生长,形成类似于骨及牙齿的纳米磷灰石晶粒结构,具有较好的生物相容性.更多还原

【Abstract】 Teeth tissue’s repair and regeneration is still one of the medical problems that need to be solved in medicine. In this paper,fluoride calcium silicate bioceramics was used to repair the acidic enamel in simulated mimetic mineralized fluids. Amelogenin inducing fluoride calcium silicate constructed mimetic mineralization structure. Through the properties characterization,the results indicated that enamel surface formed a more compacted biomimetic mineralization layer by using the amelogenin inducing fluoride calcium silicate compared with the single fluoride calcium silicate biomaterials. At the same time,its mechanical property was better than that of the fluoride calcium silicate. The particles were orderly arranged and grew along the meridional axis,and formed nanoapatite structure like bone or teeth. Mineralized layer showed a good biocompatibility.更多还原