【摘要】 目的:分析探讨中性粒细胞与淋巴细胞比值(NLR)、血小板与淋巴细胞比值(PLR)、红细胞分布宽度变异系数(RDW-CV)、平均血小板体积(MPV)在正常妊娠与子痫前期间的相关性,及MPV在子痫前期中的诊断价值。方法:选取轻度子痫前期34例、重度子痫前期57例及同期正常妊娠孕妇54名(对照组),空腹抽取静脉血,进行全血细胞分析,比较NLR、PLR、RDW-CV、血小板分布宽度(PDW)、MPV。结果:对照组与轻度子痫前期组及重度子痫前期组的MPV水平差异均具有统计学意义(P<0.05)。对照组年龄、中性粒细胞计数(N)、淋巴细胞计数、PDW、MPV水平与子痫前期组相比差异具有统计学意义(P<0.05～P<0.01)。轻度子痫前期组与重度子痫前期之间N差异具有统计学意义(P<0.05),MPV水平无差异。MPV=10.35时诊断子痫前期的敏感度为68.5%,特异度为87.0%。结论:MPV与子痫前期的发生密切相关,是诊断子痫前期的有效标志物。更多还原

【Abstract】 Objective:To investigate the correlation of neutrophil-to-lymphocyte ratio(NLR),platelet-to-lymphocyte ratio(PLR),coefficient of variation of erythrocyte distribution width(RDW-CV) and mean platelet volume(MPV) between normal pregnancy and preeclampsia,and diagnostic value of MPV in preeclampsia.Methods:The whole blood cell in 34 pregnant women with mild preeclampsia,57 pregnant women with severe preeclampsia and 54 normal pregnant women(control group) were analyzed.The NLR,PLR,RDW-CV,distribution width of platelet(PDW) and MPV among all patients were analyzed.Results:The differences of the levels of MPV among control group,mild preeclampsia group and severe preeclampsia group were statistically significant(P<0.05).The differences of the age,neutrophil count,lymphocyte count,PDW and MPV between the control group and preeclampsia group were statistically significant(P<0.05 to P<0.01).The difference of neutrophil count between mild preeclampsia group and severe preeclampsia group was statistically significant(P<0.05).The sensitivity and specificity of MPV=10.35 was 68.5% and 87.0%,respectively.Conclusions:MPV is closely correlated with to the occurrence of preeclampsia,and an effective marker for diagnosis of preeclampsia.更多还原