【摘要】 目的探讨脑出血急性期合并脑梗死的危险因素。方法按照发病后2周内弥散加权成像(diffusion weighted image,DWI)上是否有新的脑梗死灶将125例原发性脑出血患者分为2组,比较临床资料的差异。结果 21例DWI阳性者脑叶出血发生率、颅内大动脉狭窄发生率、平均血肿体积显著高于38例DWI阴性者(P<0.05)。Logistic回归分析显示入院第1 d平均动脉压降低幅度(OR=7.384,P<0.001)、脑叶出血(OR=3.124,P=0.021)及颅内大动脉狭窄(OR=5.044,P=0.027)与脑出血急性期合并新发脑梗死灶呈正相关。结论平均动脉压降低幅度、脑叶出血、颅内大动脉狭窄可增加脑出血急性期合并急性脑梗死的风险。更多还原

【Abstract】 Objective To explore the risk factors of acute primary intracerebral haemorrhage( p ICH) with ischemic brain lesions. Methods 125 p ICH patients were divided into two groups according to the presence of new ischemic lesions in diffusion weighted image( DWI) which was tested from patients within 2 weeks after onset. And the clinical data from two groups were compared. Results 21 positive patients with acute ischemic lesions had a higher rate of lobar p ICH,intracranial artery stenosis and larger mean volume of hematoma than the 38 negative patients( P <0. 05). As showed by regression,DWI lesions were positively associated with the presence of lobar ICH( OR = 2. 384,P = 0. 021),aggressive BP-lowering at the first day after admission( OR = 3. 124,P < 0. 001),and the presence of intracranial artery stenosis( OR = 5. 044,P = 0. 027). Conclusion Aggressive BP-lowering,lobar ICH,intracranial artery stenosis,and volume of hematoma would be the risk factors of p ICH with ischemic brain lesions.更多还原