Purpose To explore the diagnostic efficacy of ~(18)F-FDG PET/CT on relapse of acute leukemia. Materials and Methods Fifty-six patients with clinically suspected relapse of acute leukemia were given~(18) F-FDG PET/CT examination. With bone marrow biopsy as golden standard of intramedullary relapse, diagnostic value of multifocal and diffuse uptake in bone marrow was determined respectively. Extramedullary recurrence took pathological and clinical comprehensive judgment as golden standard. Results When the mu...