【摘要】 目的:建立同时测定肚痛丸中6种成分含量的气相色谱方法。方法:色谱柱为HP-5柱（30 m×0.32 mm,0.25μm）;采取程序升温,载气为氮气,流速为2.0 ml·min^-1,进样量为1μl,分流比为5∶1,进样口温度为280℃,检测器（FID）温度为300℃。结果:桂皮醛、乙酸龙脑酯、木香烃内酯、去氢木香内酯、厚朴酚、和厚朴酚分别在32.28⁵16.40μg·ml^-1（r=0.999 3）、27.06⁴33.00μg·ml^-1（r=0.999 2）、25.65⁴10.40μg·ml^-1（r=0.999 3）、26.10⁴17.60μg·ml^-1（r=0.999 3）、24.01³84.20μg·ml^-1（r=0.999 0）、18.32²93.10μg·ml^-1（r=0.999 4）范围内呈良好的线性关系;平均加样回收率分别为99.71%（RSD=0.67%）、99.34%（RSD=1.18%）、100.16%（RSD=0.34%）、100.40%（RSD=0.39%）、99.32%（RSD=1.22%）、99.58%（RSD=0.58%）（n=6）。结论:该方法操作简便,灵敏度高,准确度好,可为控制该制剂的质量提供依据。更多还原

【Abstract】 Objective: To establish a GC method for the imultaneous determination of cinnamaldehyde,bornyl acetate,costunolide,dehydrocostus lactone,magnolol and honokiol in Dutong pills. Methods: The determination was performed on an HP-5 column（ 30 m × 0. 32 mm,0. 25 μm） with programmed temperature. The carrier gas was nitrogen with the flow rate of 2. 0 ml·min^-1. The injection volumn was 1 μl and the sample split ratio was 5∶ 1. The inlet temperature was 280 ℃. The detector was a flame ionization detector with temperature at 300 ℃. Results: The linear ranges were 32. 28-516. 40 μg · ml^-1 for cinnamaldehyde（ r = 0. 999 3）,27. 06-433. 00 μg·ml^-1 for bornyl acetate（ r = 0. 999 2）,25. 65-410. 40 μg·ml^-1 for costunolide（ r = 0. 999 3）,26. 10-417. 60 μg·ml^-1 for dehydrocostus lactone（ r = 0. 999 3）,24. 01-384. 20 μg·ml^-1 for magnolol（ r = 0. 999 0） and 18. 32-293. 10 μg·ml^-1 for honokiol（ r = 0. 999 4）. The average recovery was 99. 71%（ RSD = 0. 67%）,99. 34%（ RSD = 1. 18%）,100. 16%（ RSD = 0.34%）,100. 40%（ RSD = 0. 39%）,99. 32%（ RSD = 1. 22%） and 99. 58%（ RSD = 0. 58%）（ n = 6）,respectively. Conclusion: The method is simple,sensitive and accurate,can be used to supplement the insufficient quality control of Dutong pills.更多还原