【摘要】 目的:对比观察纳布啡用于妇科宫腔镜手术的临床疗效。方法:择期静脉全麻下行宫腔镜手术患者60例,随机分为两组,每组30例。试验组(N组):纳布啡0.15mg/kg+丙泊酚1.5～2.0mg/kg;对照组(C组):芬太尼1.5μg/kg+丙泊酚1.5～2.0mg/kg。观察记录两组患者术后苏醒时间以及苏醒即刻(T0)、术后1h(T1)、3h(T2)的宫缩痛VAS评分和不良反应情况(包括呼吸抑制、恶心呕吐、头晕嗜睡等),以及补救镇痛药等。结果:两组患者苏醒时间无差异(P> 0.05);N组患者T0、T1时点宫缩痛VAS评分明显低于C组相应时点(P <0.05),T2时无差异(P> 0.05);其他不良反应无明显差异(P> 0.05)。结论:与芬太尼相比,纳布啡用于妇科宫腔镜手术,能明显减轻术后宫缩痛,适合该类短小手术的临床应用。更多还原

【Abstract】 Objective: To compare the clinical efficacy of nalbuphine for hysteroscopic surgery. Methods: 60 cases were randomly divided into two groups equally. The observed group(N group) was given nalbuphine and propofol; the control group(C group) was given fentany plus propofol. The recovery time, uterine contraction pain VAS scores in 1 h and 3 h after revive, adverse reactions(respiratory depression, nausea and vomiting, drowsiness, etc.) and remedial analgesics were observed. Results: There was no significant difference of the recovery time between groups(P>0.05). VAS score of contractions in N group at T0 and T1 were significantly lower than those in C group(P<0.05), with no difference at T2(P>0.05). There was no difference in other adverse reactions(P>0.05). Conclusion: Compared with fentanyl, nalbuphine for hysteroscopy surgery can significantly reduce the postoperative uterine contractions pain, suitable for short-term surgery.更多还原