【摘要】 目的:探讨自拟肝肾不足方沐足治疗糖尿病足(DF)的疗效及作用机制。方法:随机将60例DF患者分为中药组(n=30)和常规组(n=30),均给予常规对症治疗,常规组给予温水浴足,中药组给予自拟肝肾不足方沐足,观察两组疗效。结果:中药组治疗后症状积分明显低于治疗前及常规组(P<0.05);中药组和常规组的临床总有效率分别为93.33%和70.00%(P<0.05);与治疗相比,两组患者的肌电图腓总神经的MNCV和SNCV较治疗前有显著提高(P<0.05),ABI较治疗前有明显增加(P<0.05),中药组改善效果较常规组更佳(P<0.05)。结论:自拟肝肾不足方沐足治疗DF可有效改善患者足部受损神经,提高踝臂功能,临床疗效显著。更多还原

【Abstract】 Objective: To investigate the efficacy and mechanism of the Ganshen Buzu prescription(肝肾不足方) on diabetic foot. Methods: 60 patients with DF were randomly divided into the TCM medicine group and routine group, 30 cases in each group. All patients were given routine symptomatic treatment. The routine group was given feet-bath by warm water, and the TCM medicine group was feetbath by the Ganshen Buzu prescription. Results: Symptom scores were significantly lower in the TCM group than before treatment and the routine group(P<0.05). The total clinical efficacy in the TCM medicine group and the routine group were 93.33% and 70.00%, respectively(P<0.05). Compared with the treatment, the MMCV and SNCV of the common peroneal nerve in two groups were more improve than those before treatment(P<0.05), and the ABI was significantly higher than before treatment(P<0.05). The improvement effect of the TCM medicine group was better than the routine group(P<0.05). Conclusion: The Ganshen Buzu prescription can effectively improve the injured nerve in the foot the function of the ankle and arm, with good effects.更多还原