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非大面积肺栓塞治疗中应用小剂量尿激酶的可行性及治疗效果分析

An analysis of application of low dose urokinase in treating non-massive PTE

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【作者】 徐良陈鹏

【Author】 Xu Liang;

【机构】 河南省南阳市第二人民医院

【摘要】 目的:探讨非大面积肺栓塞治疗中应用小剂量尿激酶治疗的可行性。方法:选择2015年5月-2016年5月我院非大面积肺栓塞65例患者作为此次研究对象,将其分成对照组(32例)与观察组(33例)。对照组采用抗凝剂豁痰祛瘀中药治疗,观察组采用小剂量尿激酶联合豁痰祛瘀中药治疗,比较两种方式治疗的效果。结果:治疗后,观察组患者的呼吸困难VAS评分、胸痛VAS评分、P(A-a)O2、CT动脉栓塞指数均低于治疗前,PO2、PCO2明显高于治疗前,治疗前后比较具有统计学差异(P<0.05)。观察组患者的治疗有效率(28例,84.85%)明显高于对照组患者(20例,62.50%),两组间比较具有统计学差异(P<0.05)。结论:采用小剂量尿激酶联合豁痰祛瘀中药治疗非大面积肺栓塞治疗能有效地改善患者疾病状况,值得临床借鉴与推广。

【Abstract】 Objective: To explore feasibility of applying low dose urokinase in treating non-massive PTE. Methods: 65 cases were divided into the control group(32 cases) and the observation group(33 cases). The control group took the Huotan Quyu medicine( 豁痰祛瘀中药). The observation group took low dose urokinase more. Results: After treatment, VAS score of difficulty in breathing, VAS score of chest pain, P(A-a)O2 and CT arterial embolism index in the observation group were lower than those before treatment. PO2 and PCO2 were significantly higher than those before treatment(P<0.05). The efficiency in the observation group(84.85%) was significantly higher than 62.50% in the control group(P<0.05). Conclusion: Low dose urokinase plus the Huotan Quyu medicine was effective, and is worthy of clinical reference and promotion.

  • 【文献出处】 中医临床研究 ,Clinical Journal of Chinese Medicine , 编辑部邮箱 ,2018年10期
  • 【分类号】R563.5
  • 【下载频次】27
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