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中国居民病毒性肝炎流行趋势分析

Incidence and trends of viral hepatitis in China

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【作者】 刘小畅赵婷赵志梅王竞冬刘镓玮易文杨净思

【Author】 LIU Xiao-chang;ZHAO Ting;ZHAO Zhi-mei;WANG Jing-dong;LIU Jia-wei;YI Wen;YANG Jing-si;Insititute of Medical Biology,Chinese Academy of Medical Sciences;

【机构】 中国医学科学院医学生物学研究所

【摘要】 目的了解中国2004—2016年病毒性肝炎流行情况,为预防和控制病毒性肝炎提供依据。方法收集2004—2016年国家卫生和计划生育委员会发布的全国法定传染病疫情资料,对病毒性肝炎的发病情况及流行趋势进行描述性分析。结果 2004—2016年我国共报告病毒性肝炎1 918.7万例,年均发病率为110.4/10万;共报告甲肝61.6万例,乙肝1 541.0万例,丙肝202.1万例,戊肝30.7万例,未分型肝炎73.3万例,年均发病率分别为3.6/10万、88.7/10万、11.5/10万、1.8/10万和4.3/10万。我国居民病毒性肝炎发病率呈小幅下降后走平趋势,但仍然处于高位;甲肝、乙肝、未分型肝炎发病率均呈逐年下降趋势,年均下降12.1%、2.5%和11.5%;丙肝发病率呈上升趋势,年均增长14.4%;戊肝发病率在较低水平波动。病毒性肝炎年均死亡率为0.67/100万,总体呈下降趋势。结论我国居民病毒性肝炎的发病率和死亡率整体下降,丙肝发病率呈上升趋势。

【Abstract】 Objective To learn the epidemiology of viral hepatitis in China from 2004 to 2016 and to provide reference for the improvement of viral hepatitis prevention and control. Methods According to the epidemic profile of notifiable diseases in China released by the National Health and Family Planning Commission from 2004 to 2016,the incidence and trends of viral hepatitis in China during the 13 years were analyzed. Results The number of viral hepatitis case in China from 2004 to 2016 was totally19.187 million and the annual average incidence was 110.4/100 000. There were 0. 616 million hepatitis A cases,15.41 million hepatitis B cases, 2.021 million hepatitis C cases, 0.307 million hepatitis E cases and 0.733 million undifferentiated hepatitis cases, with the annual average incidence of 3.6/100 000, 88.7/100 000, 11.5/100 000, 1.8/100 000 and 4. 3/100 000,respectively. The incidence of viral hepatitis in China presented a gentle decline and flat tendency,but was still at a high level.The incidence of hepatitis A, hepatitis B and the undifferentiated hepatitis showed a downtrend with annual average declining rates of 12.1%,2.5% and 11.5%,respectively;the incidence of hepatitis C rose in an annual average growth rate of 14.4%;while the incidence of hepatitis E was characterized by fluctuation at a relatively low level. Generally,the mortality rate of viral hepatitis declined and the annual average rate was 0.67/1 000 000. Conclusion From 2014 to 2016,the morbidity and mortality of viral hepatitis in China dropped gradually,yet the occurrence of hepatitis B was still at a high level; the incidence of hepatitis C had a increasing trend.

【关键词】 病毒性肝炎发病率死亡率
【Key words】 Viral hepatitisIncidenceMortality
【基金】 国家“重大新药创制”科技重大专项(2015ZX09101031);国家十一五“重大新药创制”科技重大专项(2009ZX09504-005)
  • 【文献出处】 预防医学 ,Preventive Medicine , 编辑部邮箱 ,2018年05期
  • 【分类号】R181.3;R512.6
  • 【被引频次】75
  • 【下载频次】1200
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