【摘要】 目的评估人工肺动脉瓣重建技术在右心室流出道重建手术中的可行性。方法回顾性分析我中心自2012年2月至2016年12月之间右室流出道重建手术35例患儿术中使用人工肺动脉瓣重建技术的情况,并随访其近中期临床结果。男19例、女16例,平均接受手术年龄10岁(5个月至42岁),体重26(8～62)kg。人工肺动脉瓣重建技术类型包括:人工单瓣技术21例,人工双瓣技术6例,综合成形法8例。结果平均体外循环时间75～251(120±37)min,主动脉阻断时间32～185(72±28)min,术后呼吸机辅助时间6～68(24±18)h,重症监护室停留时间14～225(59±51)h,术后早期死亡3例均与人工肺动脉瓣重建技术无明显相关性。平均随访时间15个月。术前瓣膜反流情况:无反流22例,轻度1例、中度7例、重度3例。术后随访终点瓣膜反流情况:无瓣膜反流8例,轻度反流22例,中度反流5例,无重度反流患者。术后肺动脉瓣相关狭窄2例,均为轻度狭窄。无瓣膜相关再次手术,延迟关胸3例。术后早期死亡3例,未随访到远期死亡患者。生存32例患者,心功能评级(NYHA)Ⅰ级20例,Ⅱ级10例,Ⅲ级2例。结论在右室流出道重建手术中运用人工肺动脉瓣重建技术,可以减轻术后早期右心室容量负荷,使患者平稳度过围术期,其外科技术简便易施行,费用低廉,近中期安全性较好,远期仍需进一步观察随访。更多还原

【Abstract】 Objective To evaluate possibility and reliability of the technique of artificial pulmonary valve reconstruction in right ventricular outflow tract reconstruction. Methods We retrospectively analyzed the clinical data of 35 patients with artificial pulmonary valve reconstruction of right ventricular outflow tract reconstruction surgery in our hospital between February 2012 and December 2016. There were 35 patients with 19 males and 16 females at age of10 years ranged 5 months to 42 years and body weight of 26(8–62) kg. There were 21 patients with artificial moncusp valve, 6 patients with bicuspid technology, 8 patients with comprehensive forming method. Results Average extracorporeal circulation time was 75–251(120±37) min. Aorta blocking time was 32–185(72±28) min. ICU stay time was 14–225(59±51) hours. Breathing machine auxiliary time was 6–68(24±18) hours. There were 3 early postoperative deaths. There was no death during the long term following-up time. Thirty-two patients survived with heart function of class Ⅰ in 20 patients, class Ⅱ in 10 patients, class Ⅲ in 2 patients. Conclusion In right ventricular outflow tract reconstruction using the technique of artificial pulmonary valve reconstruction in the operation, it can reduce early postoperative right ventricular volume load. To smooth out perioperative patients, the surgical technique is simple, cheap,safe, but long-term follow-up still needs further observation.更多还原