Telomere is located at the end of chromosome and is closely related to chromosome stability in eukaryotic cell. The length of telomeres gradually decreases along with chromosome replication. Cell with over shortened telomeres ultimately end up with death.Telomerase is composed of RNA and protein and maintains telomere length. Compromised telomerase activity leads to decrease of telomere. Therefore, The activation of telomerase and length maintaining of telomereis were necessary for human tumor cells. Mutual...
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