【摘要】 雷帕霉素靶蛋白(TOR)是一种存在于真核生物中进化保守的丝氨酸/苏氨酸激酶,通过调节细胞周期、蛋白质合成、细胞能量代谢等多种途径发挥重要的生理功能。作为真核生物生长发育与免疫应答中最重要且高度保守的宏观调控者之一,TOR已成为近年生物学领域一个新的研究热点。本文主要阐述了TOR在生物中高度保守和对雷帕霉素敏感的特性,及其在拟南芥(Arabidopsis thaliana)、玉米(Zea mays)、豌豆(Pisum sativum)等植物中对生长、SnRK-TOR信号通路、糖代谢及防御反应的影响。更多还原

【Abstract】 Target of rapamycin(TOR) is a kind of evolutionarily conservative serine/threonine kinase existing in eukaryotes, and plays an important role in regulating cell cycle, protein synthesis, and cell energy metabolism. As one of the most important and highly conservative macro-regulators in the growth of eukaryote and immune response, TOR has become a new research hotspot in biology field in recent years. This paper mainly elaborates the high conservativity and sensitivity to rapamycin characteristics of TOR, and its impact on growth, sucrose nonfermentation–associated protein kinases(SnRKPT), TOR signaling pathway, glucose metabolism and defense response in plants such as Arabidopsis thaliana, Zea mays, Pisum sativum, etc.更多还原