【摘要】 目的复核本市涪城和江油部分乡镇卫生院/社区卫生服务中心生化HBsAg和HBsAb指标,分析检验结果,为两地检验质控工作提供参考依据。方法采用系统抽样方法,抽取两地项目各点984份血液标本,用ELISA法进行HBsAg和HBsAb检测,并进行Kappa检验和卡方检验。结果 984份血标本,标本不合格率为2.59%,两地标本不合格率差异有统计学意义(χ~2=26.34,P<0.05);涪城与市级检测HBsAb阳性率Kappa一致性检验差异有统计学意义(χ~2=28.59,P<0.05);江油与市级检测HBsAb阳性率Kappa一致性检验差异有统计学意义(χ~2=81,P<0.05);两地合计的HBsAg和HBsAb检测结果不符合率比较,差异有统计学意义(χ~2=144.38,P<0.05)。结论血标本不合格率涪城比江油高;市级和两区县检测结果一致性比较高;两地HBsAb不符合率较高,区县乡镇卫生院/社区卫生服务中心检验科应做好生化质控,提高标本合格率和HBsAb检测结果符合率,最终达到提高检测水平的目的。更多还原

【Abstract】 Objective Through checking biochemical indicator of HBsAg and HBsAb and analyzing the lab test result,to provide reference for biochemical quality control of community hospitals and township health centers in the two counties of Mianyang. Methods A total of 984 blood samples from community hospitals and township health centers were selected by systematic extraction method,and ELISA test was used to detect HBsAg and HBsAb for Kappa test and chi-square test. Results The false positive rate in 984 blood samples was 2. 59%,and there was statistical significance on the difference between the two counties( χ~2= 26. 34,P < 0. 05); there was statistical significance on the difference between Jiangyou and Mianyang for the positive rate of HBsAb( χ~2= 28. 59,P < 0. 05); there was statistical significance on the difference between Fuchen and Mianyang for the positive rate of HBsAb( χ~2= 81,P < 0. 05); the non-conformity rate of HBsAg and HBsAb test results were compared,and the difference was statistically significant( χ~2= 144. 38,P < 0. 05). Conclusion The failure rate of blood sample in Yucheng is higher than that in Jiangyou; the test results are highly consistent at the municipal level and the two counties; the HBsAb non-conformity rate is higher in the two places,and the laboratory of township hospitals/community health service center should do biochemical quality control,improve the qualified rate of specimens and the compliance rate of HBsAb test results,so as to improve the detection.更多还原