节点文献
猫ω干扰素研究进展
Research Progress of FeIFN-ω
【摘要】 猫ω干扰素因其较高的抗病毒、抗增殖和抗肿瘤效果以及免疫调节作用引起广泛关注与研究。结合ω干扰素相关研究结果,综述猫ω干扰素的结构特征、生物学活性以及抗病毒的作用机制,综合分析其在临床上对FCV、FHV-1、FIV、FCGS及FIP等几种常见猫病毒病的治疗效果,以期为临床上寻求新型有效的动物抗病毒药物提供参考。
【Abstract】 With the developing of the research on FeIFN-ω,its high antiviral,antiproliferative and antitumor effects,as well as immune regulation,has attracted widespread attention and research. Based on the related research results of IFN-ω,the structure,biological activity and antiviral mechanism of FeIFN-ω were reviewed in the paper. The therapeutic effects of FeIFN-ω on several common feline viral diseases,such as FCV,FHV-1,FIV,FCGS and FIP,were analyzed comprehensively in order to seek new and effective animal antiviral drugs in clinic.
【关键词】 猫ω干扰素;
抗病毒活性;
作用机制;
临床应用;
【Key words】 FeIFN-ω; antiviral activity; mechanism; clinical research;
【Key words】 FeIFN-ω; antiviral activity; mechanism; clinical research;
【基金】 十三五国家重点研发项目(2017YFD0501703,2016YFD0501002)
- 【文献出处】 中国兽药杂志 ,Chinese Journal of Veterinary Drug , 编辑部邮箱 ,2018年12期
- 【分类号】S859.1
- 【被引频次】3
- 【下载频次】294