【摘要】 目的评价重复低能量强脉冲光治疗痤疮的疗效及安全性。方法 80例痤疮患者,随机分为试验组和对照组,每组40例。试验组采用重复低能量强脉冲光连续治疗2次,对照组采用正常能量强脉冲光治疗1次。治疗后评价两组患者的临床疗效及不良反应。结果两组患者治疗后的皮疹均明显改善。试验组痊愈率为57.5%,总有效率为85.0%;对照组痊愈率为32.5%,总有效率为75.0%。试验组痊愈率高于对照组,差异有统计学意义(P<0.05),试验组总有效率略高于对照组,但差异无统计学意义(P>0.05)。试验组疼痛评分低于对照组,差异有统计学意义(P<0.05)。两组红斑、水疱、继发性色素沉着等不良反应发生率比较差异无统计学意义(P>0.05)。结论重复低能量强脉冲光治疗痤疮疗效优于单次高能量强脉冲光,且不增加不良反应。更多还原

【Abstract】 Objective To evaluate the efficacy and safety of repeated low-energy intense pulsed light in the treatment of acne. Methods A total of 80 acne patients were randomly divided into experimental group and control group, with 40 cases in each group. The experimental group received repeated low-energy intense pulsed light for 2 consecutive times, and the control group received normal energy intense pulsed light for 1 time. Evaluation were made on clinical efficacy and adverse reactions after treatment between two groups. Results The rash in the two groups was significantly improved after treatment. The experimental group had cure rate as 57.5% and total effective rate as 85.0%, while the control group had cure rate as 32.5% and total effective rate as 75.0%. The experimental group had higher cure rate than the control group, and the difference was statistically significant(P<0.05). The experimental group had little higher total effective rate than the control group, but the difference was not statistically significant(P>0.05). The experimental group had lower pain score than the control group, and the difference was statistically significant(P<0.05). Both groups had no statistically significant difference in incidence of adverse reactions of erythema, blisters, secondary pigmentation(P>0.05). Conclusion Repeated low-energy intense pulsed light provides better efficacy than single high-energy intense pulsed light without increasing adverse reactions.更多还原