【摘要】 利用傅里叶变换红外光谱与傅里叶变换拉曼光谱技术对甾体激素类药丙酸氯倍米松进行分子振动光谱的表征,并结合二阶导数谱进一步提高谱图的分辨率。结果表明结合两种分子光谱的特点能对结构复杂药物的谱图进行了更准确的谱峰归属解析,提供了丙酸氯倍米松完整的分子振动光谱特征,为药物在无损状态下的结构信息表征提供了依据。更多还原

【Abstract】 FT-IR and FT-Raman are applied to characterize the molecular vibrational spectra of Clobetasol Propionate.The second derivative spectra are used to enhance the spectra’s resolution.The results show that the spectra’s bands of Clobetasol Propionate can be more sufficiently assigned by combining two kinds molecular spectra.The research proves that the structure information of medicine can be obtained under no-destructive state.更多还原