Proteomics is an emerging discipline to apply multiple technical approaches for studying the proteomics. It has an ability to identify various kinds of signal transduction complexes and paths in stem cell differentiation. First, various approaches can be taken for obtaining sufficient tumor stem cells required for proteomic analysis; second, it is possible to make use of subcellular isolation technique as a tool of proteomic analysis; moreover, proteomic method can be used for identifying tumor stem cell no...