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脱水剂在急性脊髓损伤中的应用进展

Application Progress of Dehydrating Agent in Acute Spinal Cord Injury(review)

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【作者】 张超李建军杨德刚杨明亮杜良杰张文豪刘长彬李大鹏胡安明秦川

【Author】 ZHANG Chao;LI Jian-jun;YANG De-gang;YANG Ming-liang;DU Liang-jie;ZHANG Wen-hao;LIU Chang-bin;LI Da-peng;HU An-ming;QIN Chuan;Capital Medical University School of Rehabilitation Medicine;Department of Spinal and Neural Function Reconstruction, Beijing Bo’ai Hospital, China Rehabilitation Research Center;Center of Neural Injury and Repair, Beijing Institute for Brain Disorders;Beijing Key Laboratory of Neural Injury and Rehabilitation;Department of Neurosurgery, Beijing Bo’ai Hospital, China Rehabilitation Research Center;

【机构】 首都医科大学康复医学院中国康复研究中心北京博爱医院脊柱脊髓神经功能重建科北京脑重大疾病研究院神经损伤与修复研究所北京市神经损伤与康复重点实验室中国康复研究中心北京博爱医院神经外科

【摘要】 急性脊髓损伤(ASCI)可分为原发性损伤和继发性损伤。脊髓水肿对脊髓继发性损伤的发展至关重要。脊髓水肿主要分为细胞毒性水肿和血管源性水肿。脱水剂在ASCI后水肿的治疗中作用明显。本文主要介绍甘露醇、高渗盐水、甘油果糖、呋塞米、人血白蛋白、白藜芦醇等脱水剂在ASCI治疗中的应用进展。

【Abstract】 Acute spinal cord injury(ASCI) can be divided into primary injury and secondary injury. Spinal cord edema is important for the development of secondary injury after ASCI. Spinal cord edema can be mainly divided into cytotoxic edema and angioedema. The application of dehydrating agents in the treatment of acute spinal cord injury is obvious. This article described the application of mannitol, hypertonic saline, glycerol fructose, furosemide, human serum albumin, resveratrol and other dehydrating agents in the treatment of ASCI.

【关键词】 脊髓损伤水肿脱水剂综述
【Key words】 spinal cord injuryedemadehydrating agentreview
【基金】 中央级公益性科研院所基本科研业务费专项资金项目(No.2016CZ-4);中国康复研究中心课题(No.2012-1;No.2013-7)~~
  • 【文献出处】 中国康复理论与实践 ,Chinese Journal of Rehabilitation Theory and Practice , 编辑部邮箱 ,2018年04期
  • 【分类号】R651.2
  • 【被引频次】4
  • 【下载频次】312
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