Antibodies were produced by using the hybridoma cell line QH12,and the highly sensitive immune colloidal gold reagent strip was thus prepared. The lowest detection limits of these stripes for lomefloxacin,ofloxacin,norfloxacin,pefloxacin were 2. 0,2. 5,2. 5,5. 0 ng·m L~(-1),respectively. The colloidal gold rapid test methods( GICT) for determination of quinolones residues in aquatic products were developed through optimization of sample pretreatment. Detection results of GICT were further compared with that...