【摘要】 目的观察振动正压呼气(OPEP)排痰对慢阻肺急性加重患者肺康复的影响。方法选择2017年6月~2018年1月在我科治疗的慢阻肺急性加重患者120例。将患者随机分为对照组和治疗组,对照组给予止咳化痰、解痉平喘及抗感染等常规治疗,治疗组在对照组常规治疗基础上加用振动正压呼气排痰装置治疗1周。观察两组患者治疗后第1、3、7天痰的变化(痰量、痰液颜色、痰液粘稠度),观察两组患者治疗后肺功能的变化:第一秒用力呼气容积(FEV1),第一秒用力呼气容积占预计值的百分比(FEV1%pred)。结果治疗组患者第1~3天平均排痰量较对照组明显增多(P<0.05);治疗组患者第3天痰色评分较对照组明显降低(P<0.05);治疗组第3天痰液粘稠度较对照组显著下降(P<0.05)。治疗组第3天FEV1及FEV1%pred较对照组明显升高,差异有统计学意义(P<0.05)。结论振动正压呼气治疗法可有效促进慢阻肺急性加重患者早期排痰,改善患者肺功能状况。更多还原

【Abstract】 Objective To observe the influence of oscillatory positive expiratory pressure(OPEP) to the sputum expectoration on patients with acute exacerbation of chronic obstructive pulmonary disease(AECOPD). MethodsSelected 120 patients diagnosed with AECOPD and accepted medicine treatment in our hospital from Jun 2017 to Jan 2018.The patients were divided into treatment group and control group randomly,and all of them were given the routine treatment of antiasthma,relieving cough,reducing sputum and anti-infection.The treatment group also accepted oscillatory positive expiratory pressure to assist sputum expectoration for seven days.Observed the two groups variant of volume of sputum,the colour and viscosity of their sputum at the first, third and seventh day after treatment. Observed variant of pulmonary function after treatment,recorded the values of forced expired volume in one second(FEV1) and forced expired volume in one second percentage of expected value(FEV1%pred). Results The average volume of sputum from the first day to the third day in the treatment group increased apparently compared with the control group,the colour score and viscosity of sputum decreased apparently at the third day compared with the control group(P<0.05).The pulmonary function(FEV1,FEV1%pred)increased apparently at the third day compared with the control group(P<0.05). Conclusion OPEP can effectively promote AECOPD patients to excrete sputum, and is beneficial to the pulmonary function of AECOPD.更多还原