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纳洛酮在治疗急性脑外伤中的疗效观察

Therapeutic Effect of Naloxone in the Treatment of Acute Traumatic Brain Injury

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【作者】 张庆伟

【Author】 ZHANG Qing-wei;Emergency Surgery,Jilin Qianwei Hospital;

【机构】 吉林省前卫医院急诊外科

【摘要】 目的观察分析纳洛酮在临床中治疗急性脑外伤患者的效果。方法随机抽取2016年5月至2018年3月在我院完成治疗的82例急性脑外伤患者,根据治疗方式进行分组,对照组(n=41)行常规药物方式治疗,观察组(n=41)行纳洛酮治疗,对两组患者治疗前后神经功能缺损情况、格拉斯哥评分情况进行评价与比较。结果治疗前,比较两组患者神经功能缺损情况、格拉斯哥评分情况(P> 0.05);治疗后,同对照组进行比较,观察组上述两项情况均较对照组佳(P<0.05)。结论在治疗急性脑外伤患者的时候,选择纳洛酮的治疗效果较常规药物方式显著,能够有效改善神经功能以及昏迷指数情况,在临床中具有可观的价值,值得推广。

【Abstract】 Objective To observe the effect of naloxone in the treatment of patients with acute traumatic brain injury. Methods Eighty-two patients with acute traumatic brain injury who underwent treatment in our hospital from May 2016 to March 2018 were randomly selected. The patients were divided according to the treatment mode. The control group(n=41) was treated with conventional drugs. The observation group( n=41) Naloxone treatment, evaluation and comparison of neurological deficits and Glasgow scores before and after treatment in the two groups. Results Before treatment, the neurological deficits and Glasgow scores were compared between the two groups(P>0.05). After treatment, compared with the control group, the above two cases were better than the control group(P< 0.05). Conclusion In the treatment of patients with acute traumatic brain injury, the treatment effect of naloxone is more significant than that of conventional drugs. It can effectively improve the neurological function and the coma index. It has considerable value in clinical and is worthy of promotion.

【关键词】 急性脑外伤纳洛酮NIHSS
【Key words】 Acute brain injuryNaloxoneNIHSS
  • 【分类号】R651.15
  • 【下载频次】29
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