【摘要】 目的:分析西安市冠心病(CHD)患者膳食脂肪酸供能比与血脂水平的相关关系。方法:选取西安市三级甲等医院的CHD患者;采用膳食频率调查表,根据每日食物摄入种类及数量计算各种膳食脂肪酸供能比;测定体格指标和空腹血脂水平;采用协方差分析探讨CHD患者膳食脂肪酸供能比与血脂水平的相关关系。结果:本次调查共纳入符合要求的研究对象152名,平均年龄60. 91±10. 94岁,饱和脂肪酸(SFA)、单不饱和脂肪酸(MUFA)和多不饱和脂肪酸(PUFA)供能比分别为7. 9%±2. 4%、16. 6%±7. 8%、11. 4%±5. 6%。在校正混杂因素后,膳食MUFA供能比与血清Apo A呈正相关(P <0. 05);低密度脂蛋白胆固醇(LDL-C)和低密度脂蛋白胆固醇/高密度脂蛋白胆固醇(LDL-C/HDL-C)比值随膳食MUFA供能比上升而下降(P <0. 05)。膳食SFA和PUFA供能比分别与LDL-C、HDL-C等间无显著相关性(P> 0. 05)。结论:CHD患者膳食MUFA供能比与血脂水平相关,提示提高膳食MUFA供能比,对改善CHD患者血脂水平具有重要作用。更多还原

【Abstract】 Objective To investigate the associations between dietary fatty acid energy ratio and biomarker levels in patients with coronary heart disease in Xi’an city. Method In this cross-sectional survey study,patient,who was diagnosed with coronary heart disease in two tertiary hospitals in Xi’an city was randomly enrolled. Quantitative food-frequency questionnaires were conducted for subjects,the fatty acid energy ratio were calculated according to the type and amount of food intake. The physical index and fasting blood lipid level were measured. Covariance analysis was used to explore the relation between dietary fatty acid energy ratio and serum lipids in patients with coronary heart disease. Result Totally 98 male and 54 female with coronary heart disease were enrolled. The average age was 60. 91 ± 10. 94 years. Saturated fatty acid( SFA),monounsaturated fatty acid( MUFA) and polyunsaturated fatty acid( PUFA) energy ratios were7. 9% ± 2. 4%,16. 6% ± 7. 8%,11. 4% ± 5. 6%,respectively. After adjustment for confounding factors,the dietary MUFA energy ratio was positively correlated with serum Apo A( P < 0. 05),and LDL-C and the ratio of LDL-C/HDL-C decreased with the increase of dietary MUFA( P < 0. 05). SFA energy ratio,and PUFA energy ratio were not related to blood lipid levels,respectively( P > 0. 05).Conclusion The dietary energy supply of MUFA in patients with coronary heart disease is related to the level of blood lipids,suggesting that increasing the energy supply ratio of dietary MUFA may be important for improving blood lipids.更多还原