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长链非编码RNA与人脑胶质瘤关联性的研究进展
Correlation between Lnc RNA with glioma
【摘要】 长链非编码RNA(LncRNA)是一种必需表观遗传调节因子,在脑组织肿瘤的产生和恶性进展过程中具有关键作用,特别是参与了脑胶质瘤的发生与发展。为了解LncRNA在脑胶质瘤中的潜在功能,该文章重点讨论几种特殊的LncRNA的作用机制和临床意义,进一步探讨LncRNA在人脑胶质瘤中的诊断与治疗前景。
【Abstract】 Long-chain non-coding RNA(LncRNA) is an essential epigenetic regulator that plays a key role in tumoxrigenesis and malignant progression of brain tissue,especially involved in the development and progression of glioma.In order to understand the potential function of LncRNA in gliomas,this article focuses on the mechanism and clinical significance of several specific LncRNAs and further explores the potential of LncRNA in the diagnosis and treatment of human gliomas.
【关键词】 脑胶质瘤;
LncRNA HOTAIR;
LncRNA H19;
LncRNA CRNDE;
LncRNA CASC2;
LncRNA XIST;
【Key words】 Glioma; LncRNA HOTAIR; LncRNA H19; LncRNA CRNDE; LncRNA CASC2; LncRNA XIST;
【Key words】 Glioma; LncRNA HOTAIR; LncRNA H19; LncRNA CRNDE; LncRNA CASC2; LncRNA XIST;
- 【文献出处】 中国当代医药 ,China Modern Medicine , 编辑部邮箱 ,2018年06期
- 【分类号】R739.41
- 【被引频次】6
- 【下载频次】179